Results 141 to 150 of about 51,303 (237)

Comet assay in myelodysplastic syndromes

Revista Brasileira de Hematologia e Hemoterapia, 2012
Paulo Florentino Teixeira Neto, Ronald Feitosa Pinheiro, Romélia Pinheiro Gonçalves   +2 more
doaj   +1 more source

The Comet Assay in Drosophila: A Tool to Study Interactions between DNA Repair Systems in DNA Damage Responses In Vivo and Ex Vivo. [PDF]

Cells, 2023
Rodríguez R, Gaivão I, Aguado L, Espina M, García J, Martínez-Camblor P, Sierra LM.   +6 more
europepmc   +1 more source

The Redox Activity of Protein Disulphide Isomerase Functions in Non‐Homologous End‐Joining Repair to Prevent DNA Damage

Aging Cell, EarlyView.
Schematic diagram illustrating the protective role of protein disulphide isomerase (PDI) against DNA damage via non‐homologous end‐joining (NHEJ), which repairs double stranded DNA breaks (DSBs). Induction of DNA damage results in the formation of γH2AX and p53‐binding protein 1 foci during NHEJ repair of DSBs.
Sina Shadfar, Fabiha Farzana, Sayanthooran Saravanabavan, Ashley M. Rozario, Marta Vidal, Cyril Jones Jagaraj, Sonam Parakh, Esmeralda Paric, Kristy C. Yuan, Mariana Brocardo, Donna R. Whelan, Angela S. Laird, Julie D. Atkin   +12 more
wiley   +1 more source

Toxische Wirkung von Schadstoffen auf Fischzellen. Bestimmung von DNA-Strangbrüchen mit dem Comet-Assay [PDF]

, 1998
The alkaline comet assay is a method of detecting DNA strand breaks and alkali labile sites in individual cells. The method was used to detect DNA strand breaks in isolated blood cells (leukocytes) of carp (Cyprius carpio).
Kammann, Ulrike
core  

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Genotoxicity Evaluation of Metformin in Freshwater Planarian Dugesia japonica by the Comet Assay and RAPD Analysis. [PDF]

Biomed Res Int, 2022
Yin D, Xu Z, Feng M, Zhao Z, Chen D, Song L.   +5 more
europepmc   +1 more source

Role of intra‐individual variation in the detection of thresholds for DFI and for misclassification rates: A retrospective analysis of 14,775 SCSA® tests

Andrology, EarlyView.
Abstract Background Sperm DNA damage is associated with reduced male fertility after natural conception and intrauterine insemination. However, the impact on in vitro fertilization (IVF) and especially intracytoplasmic sperm injection (ICSI) treatments is still unclear.
Preben Christensen, Robert Fischer, Wolfgang Schulze, Vera Baukloh, Kimberly Kienast, Graham Coull, Erik T. Parner   +6 more
wiley   +1 more source

Effectiveness and safety of repeated photodynamic therapy in recurrent central serous chorioretinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate anatomical and functional outcomes after a second photodynamic therapy (PDT) in patients with central serous chorioretinopathy (CSC), who had a recurrence of subretinal fluid (SRF) after a previously successful PDT. Methods In this multicentre retrospective cohort study, we included patients with CSC who underwent a second ...
F. M. van den Tillaart, A. Komrojan, C. B. Hoyng, J. P. Martinez Ciriano, S. Yzer   +4 more
wiley   +1 more source

A High-Throughput Comet Assay Approach for Assessing Cellular DNA Damage. [PDF]

J Vis Exp, 2022
Ji Y, Karbaschi M, Abdulwahed A, Quinete NS, Evans MD, Cooke MS.   +5 more
europepmc   +1 more source

Elucidating the Role and Mechanism of Alpha‐Enolase in Senescent Amelioration via Metabolic Reprogramming

Cell Proliferation, EarlyView.
KB2764 interacted with alpha‐enolase (ENO1) and pyruvate kinase M (PKM), ultimately leading to PKM phosphorylation of ENO1. KB2764 consequently increased mitochondrial ATP production and decreased glycolysis dependence. Furthermore, the action of KB2764 extends its application to extend the lifespan of Caenorhabditis elegans.
Yun Haeng Lee, Hyunwoong Lim, Gyungmin Kim, Geonhee Jang, Myeong Uk Kuk, Ji Ho Park, Jee hee Yoon, Yoo Jin Lee, Duyeol Kim, Byeonghyeon So, Minseon Kim, Hyung Wook Kwon, Youngjoo Byun, Joon Tae Park   +13 more
wiley   +1 more source