Results 141 to 150 of about 1,931,388 (325)

The correlation between sperm DNA methylation and DNA damage: a comparison of comet and TUNEL

Frontiers in Reproductive Health
ObjectiveTo evaluate the relationship between sperm DNA methylation and DNA damage as determined by the comet or TUNEL assays.DesignRetrospective research study.SettingUniversity-based andrology and in vitro fertilization (IVF) laboratory.Patient(s)Data ...
Hailey Zimmerman, Tim Jenkins
doaj   +1 more source

Optimizing the Comet Assay-Based In Vitro DNA Repair Assay for Placental Tissue: A Pilot Study with Pre-Eclamptic Patients. [PDF]

Int J Mol Sci, 2023
Mircheva A, Vangrieken P, Al-Nasiry S, van Schooten FJ, Godschalk RWL, Langie SAS.   +5 more
europepmc   +1 more source

DNA damage and repair in Arabidopsis thaliana as measured by the comet assay after treatment with different classes of genotoxins [PDF]

, 2001
Merten Menke, I‐Peng Chen, Karel J. Angelis, Ingo Schubert   +3 more
openalex   +1 more source

Systematic identification of existing core outcomes related to preterm birth and the development of a core outcome set for preterm birth in Aotearoa New Zealand

Pediatric Investigation, EarlyView.
We have used a systematic approach to determine a preterm birth core outcome set, informed by people with lived experience, perinatal healthcare professionals, and researchers. This will be recommended in preterm birth research and clinical care in Aotearoa New Zealand and for consideration internationally.
Briar Hunter, Lisa Dawes, Lynn Sadler, Jordon Wimsett, Sue Tutty, Matthew Moore, Malcolm R Battin, Katie M Groom   +7 more
wiley   +1 more source

Reconstructed human intestinal comet assay, a possible alternative in vitro model for genotoxicity assessment. [PDF]

Mutagenesis, 2023
Hughes CO, Lim HK, Tan JCW, Leavesley DI, Smith BPC.   +4 more
europepmc   +1 more source

Genotoxic Effects of the Alkaloids Harman and Harmine Assessed by Comet Assay and Chromosome Aberration Test in Mammalian Cells in vitro [PDF]

, 2001
Jane Marlei Boeira, Juliana da Silva, Bernardo Erdtmann, João Antônio Pêgas Henriques   +3 more
openalex   +1 more source

Defining the parameters of comet assay for reliably detecting DNA damage as a marker of X‐ray based irradiation in insects treated with non‐lethal doses for export fruit sanitation

Pest Management Science, EarlyView.
Houseflies, clover root weevils, and mangoes were used to demonstrate the comet assay's adaptability. Our findings indicate that the comet assay can reliably detect irradiation‐induced DNA damage in both insects and fruit. However, the assay parameters require careful adjustment to account for differences in insect tissue types and life stages ...
Ela Hiszczynska‐Sawicka, Nicola K. Richards, Jill L. Gibson, Chikako van Koten, Disna Gunawardana, Karen F. Armstrong   +5 more
wiley   +1 more source

Clinical modeling of motor function to predict treatment efficacy and enable in silico treatment comparisons in infantile‐onset Pompe disease

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Abstract Infantile‐onset Pompe disease (IOPD) is a rare, deadly, quickly‐progressing degenerative disease. Even with life‐sustaining treatment (e.g., alglucosidase alfa [ALGLU]), many patients experience continued motor impairment. The Mini‐COMET trial evaluated avalglucosidase alfa (AVAL) versus ALGLU on motor and other outcomes in IOPD.
Fatiha Rachedi, Rana Jreich, Susan Sparks, Atef Zaher, Kristina an Haack, Alicia Granados, Zhaoling Meng   +6 more
wiley   +1 more source

Evaluation of DNA repair capacity in parents of pediatric patients diagnosed with autism spectrum disorder using the comet assay procedure. [PDF]

IBRO Neurosci Rep, 2023
Akouchekian M, Alizadeh R, Beiranvandi F, Dehghan Manshadi M, Taherizadeh F, Hakim Shooshtari M.   +5 more
europepmc   +1 more source

Assessment of genotoxic damage by the comet assay in white storks (Ciconia ciconia) after the Donana Ecological Disaster [PDF]

, 2001
Nuria Pastor
openalex   +1 more source