Results 181 to 190 of about 889,387 (243)

Developing a core outcome set for generalized anxiety disorder during the perinatal period: Identifying core treatment outcomes in perinatal anxiety

open access: yesBritish Journal of Clinical Psychology, Volume 65, Issue 4, Page 1094-1113, November 2026.
Abstract Background Generalized anxiety disorder during the perinatal period (pGAD) is highly prevalent and associated with adverse outcomes for both mother/birthing person (BP) and child. Yet, most treatment studies rely on researcher‐selected outcomes that may not reflect patient priorities.
Emma M. Stallwood   +6 more
wiley   +1 more source

Impact Crater Hydrothermal Systems Support Rapid Microbial Enrichment and Diverse Metabolic Potential

open access: yesGeobiology, Volume 24, Issue 6, November/December 2026.
ABSTRACT Impact crater hydrothermal systems, formed after asteroid and comet impacts, have been proposed as promising habitats for life on early Earth and as key targets in the search for life on planetary bodies such as Mars, since they provide liquid water and active geochemical turnover.
Sabrina M. C. Hardy   +8 more
wiley   +1 more source

Constraining Fault Kinematics and India‐Tarim Convergence Partitioning in Southwestern Tibet With Geodetic Block Modeling

open access: yesGeophysical Research Letters, Volume 53, Issue 20, 28 October 2026.
Abstract How the convergent strain between the India Plate and the Tarim basin is partitioned by active faults and off‐fault deformation in southwestern Tibet is poorly understood due to limited knowledge of strain localisation and fault kinematics. In this study, we derive high‐resolution velocity fields for the southwestern Tibetan Plateau using both
Dehua Wang   +4 more
wiley   +1 more source

Measurements of the Size and Physical Properties of Marine Particles Using Atomic Force Microscopy: Implications for Marine Biogeochemical Cycles

open access: yesGeophysical Research Letters, Volume 53, Issue 19, 16 October 2026.
Abstract Particle size and physical properties such as stiffness and adhesiveness affect sinking velocity and flux in the ocean, yet conventional two‐dimensional measurements lack accuracy and mechanical information. In this study, we applied atomic force microscopy (AFM) to quantify three‐dimensional size and physical properties of marine particles ...
Y. Yamada   +4 more
wiley   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, Volume 38, Issue 57, 13 October 2026.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang   +11 more
wiley   +1 more source

Reversing Temozolomide Resistance in Glioblastoma Based on Cuproptosis‐Mediated Positive Feedback Loop

open access: yesAdvanced Science, Volume 13, Issue 57, 14 October 2026.
To effectively reverse TMZ resistance, this work proposes a cuproptosis‐mediated positive feedback loop that integrates mitochondrial dysfunction, ATP depletion, AMPK‐p53 signaling, and glycolytic inhibition, ultimately amplifying cell death. This cuproptosis‐mediated feedback loop simultaneously disrupts multiple resistance pathways in GBM, including ...
Wenjie Feng   +9 more
wiley   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo   +10 more
wiley   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun   +7 more
wiley   +1 more source

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

open access: yesThe Anatomical Record, Volume 309, Issue 10, Page 2698-2724, October 2026.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille   +6 more
wiley   +1 more source

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