Results 181 to 190 of about 33,064 (290)

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source

Elucidation of Potential Genotoxicity of MXenes Using a DNA Comet Assay. [PDF]

ACS Appl Bio Mater
Kyrylenko S, Chorna I, Klishchova Z, Yanko I, Roshchupkin A, Deineka V, Diedkova K, Konieva A, Petrichenko O, Kube-Golovin I, Wennemuth G, Coy E, Roslyk I, Baginskiy I, Zahorodna V, Gogotsi O, Chacon B, Cartarozzi LP, Oliveira ALR, Iatsunskyi I, Gogotsi Y, Pogorielov M.   +21 more
europepmc   +1 more source

Slightly increased level of DNA migration in the comet assay: does statistical significance equal biological significance? [PDF]

Mutagenesis
Møller P, Collins A, Rodriguez-Garraus A, Langie SAS, Godschalk R, Azqueta A.   +5 more
europepmc   +1 more source

Comet assay for quantification of the increased DNA damage burden in primary human chondrocytes with aging and osteoarthritis. [PDF]

Aging Cell, 2022
Copp ME, Chubinskaya S, Bracey DN, Shine J, Sessions G, Loeser RF, Diekman BO.   +6 more
europepmc   +1 more source

Inter-laboratory calibration of different Comet Assay protocols

, 2007
Ceretti E, Mussi F, DOMINICI, LUCA, Buschini A, VILLARINI, Milena, MONARCA, Silvano, Rossi C, Poli P, Feretti D, MORETTI, Massimo   +9 more
core   +1 more source

Rapid and Accurate Genotoxicity Assessment Using the Neutral Comet Assay in <i>Cyprinus carpio</i> Cells. [PDF]

Life (Basel)
So B, Park JH, Kim M, Lee H, Yoon JH, Lee YJ, Kim D, Kwon HW, Park J, Han T, Lee YH, Park JT.   +11 more
europepmc   +1 more source

Antioxidant and genoprotective effects of osthole against cadmium-induced DNA damage: an in vitro study using comet assay. [PDF]

Res Pharm Sci, 2022
Vahidifar E, Sajjadi SE, Etebari M.
europepmc   +1 more source

Chemical Exposures, DNA Methylation and Whole Blood DNA Damage in Pet Golden Retrievers

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Canine multicentric lymphoma (CL) is a common and typically fatal cancer among dogs. Although certain breeds have a higher incidence of CL, its environmental risk factors remain uncertain. Exposures to herbicides and volatile organic compounds (VOCs) associate with non‐Hodgkin lymphoma in people.
Ashleigh N. Tindle, Mark E. Berres, Lauren Baker, Zhuonan Wu, Brenna Swafford, Julia Labadie, Lauren A. Trepanier   +6 more
wiley   +1 more source

Defining the parameters of comet assay for reliably detecting DNA damage as a marker of X-ray based irradiation in insects treated with non-lethal doses for export fruit sanitation. [PDF]

Pest Manag Sci
Hiszczynska-Sawicka E, Richards NK, Gibson JL, van Koten C, Gunawardana D, Armstrong KF.   +5 more
europepmc   +1 more source

CometAnalyser: A user-friendly, open-source deep-learning microscopy tool for quantitative comet assay analysis. [PDF]

Comput Struct Biotechnol J, 2022
Beleon A, Pignatta S, Arienti C, Carbonaro A, Horvath P, Martinelli G, Castellani G, Tesei A, Piccinini F.   +8 more
europepmc   +1 more source