Results 211 to 220 of about 850,969 (288)

The Comet Assay as a Tool in Human Biomonitoring Studies of Environmental and Occupational Exposure to Chemicals-A Systematic Scoping Review. [PDF]

Toxics
Ladeira C, Møller P, Giovannelli L, Gajski G, Haveric A, Bankoglu EE, Azqueta A, Gerić M, Stopper H, Cabêda J, Tonin FS, Collins A.   +11 more
europepmc   +1 more source

Assessment of Genotoxic, Oxidative Stress and Histopathological Effects of Azo Dye Acid Red 119 on Blood and Gill of Freshwater Fish Channa punctata

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Azo dye Acid Red 119 exerts marked DNA damage, oxidative stress, antioxidant enzymatic, and histopathological alterations in the blood and gills of freshwater fish Channa punctata, underscoring the urgent need for stricter effluent regulation and sustainable treatment strategies in textile industries.
Harpal Kaur, Divya Saini, Aditi Khanna, Pooja Chadha   +3 more
wiley   +1 more source

Comparison of the genotoxicity of propofol and desflurane using the comet assay in the lymphocytes of patients who underwent lumbar discectomy: A randomized trial. [PDF]

Saudi Med J
Toker MK, Altiparmak B, Gursoy G, Uysal AI, Dede G, Gundogdu G, Dodurga Y, Ugur B.   +7 more
europepmc   +1 more source

Sclareol Inhibit Cell Growth and Induces Apoptosis via Activation of p53/p21 Signaling Pathways in Human Oral Squamous Cell Carcinoma Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The Schematic representation of the possible molecular mechanism of sclareol induces apoptosis through p53 and p21‐associated signaling in KB cells. ABSTRACT One of the most common prevalent forms of cancer in the world is oral squamous cell carcinoma (OSCC).
Anandhi Nallu, Suresh Kathiresan, Theerthu Azhamuthu, Hemavardhani Ramadoss, Nihal Ahamed Abulkalam Asath, Pugazhendhi Ravichandran, Rajeswari Vasu   +6 more
wiley   +1 more source

Agricultural exposures and DNA damage in PBMC of female farmers measured using the alkaline comet assay. [PDF]

Int Arch Occup Environ Health
Evenden P, Vandoolaeghe Q, Lecluse Y, Gac AC, Delépée R, Weiswald LB, Boutet-Robinet E, Boulanger M, Bonassi S, Lebailly P, Meryet-Figuière M.   +10 more
europepmc   +1 more source

Host‐to‐Pathogen Transfer of Neutrophil Components via Extracellular Vesicles Shields Candida albicans From Immune Attack in Human Blood

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Neutrophils release extracellular vesicles (EVs) in response to Candida albicans, and these EVs bind to the fungus in a complement‐dependent manner while carrying neutrophil surface markers and antimicrobial proteins. Despite this cargo, EV coating does not inhibit fungal growth but markedly reduces neutrophil phagocytic uptake in purified‐cell assays ...
Jennifer J. Patitz, Natalie E. Nieuwenhuizen, Anastasia Solomatina, Yann Bachelot, Thomas Krüger, Carl‐Magnus Svensson, Stephanie Hoeppener, Ann‐Kathrin Zimmermann, Matthew G. Blango, Ronny Martin, Olaf Kniemeyer, Theresa Lange, Axel A. Brakhage, Marc Thilo Figge, Oliver Kurzai, Kerstin Hünniger‐Ast   +15 more
wiley   +1 more source

Galectin‐4: A Novel Mediator of Human Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 3, September 2026.
Galectin‐4 correlates with intervertebral disc degeneration, independent of age, sex, or underlying pathology. Functionally, it activates NF‐κB signaling and induces pro‐inflammatory and matrix‐degrading responses, with stronger effects in nucleus pulposus cells, identifying it as a novel molecular player in disc degeneration.
Christine Strauss, Daniel Djojic, Johannes Stadlmann, Josef Georg Grohs, Jürgen Alphonsus, Sebastian Schmidt, Sabine André, Katharina Margareta Pichler, Sara Savic‐Ivanovic, Melanie Cezanne, Mario Rothbauer, Reinhard Windhager, Stefan Toegel   +12 more
wiley   +1 more source

Visualizing DNA single- and double-strand breaks in the Flash comet assay by DNA polymerase-assisted end-labelling. [PDF]

Nucleic Acids Res
Bivehed E, Hellman B, Wenson L, Stenerlöw B, Söderberg O, Heldin J.   +5 more
europepmc   +1 more source

Early Local Treatment Delays Multiple Metastases in Non‐Small Cell Lung Cancer With Solitary Distant Metastasis: A Multicenter Retrospective Cohort Study

MedComm, Volume 7, Issue 9, September 2026.
In NSCLC patients with solitary distant metastasis (SDM), early local treatment significantly delays the progression to multi‐metastasis by 14 months (HR = 0.55) compared to delayed or no treatment. This multicenter cohort study highlights SDM as an indolent state, emphasizing the critical time window for effective local intervention. .
Kang Miao, Siyu Lei, Xiaobin Zheng, Shanshan Yang, Yujing Li, Sihui Chen, Qian Miao, Longfeng Zhang, Zihua Zou, Haipeng Xu, Gen Lin   +10 more
wiley   +1 more source

DUSP12 Regulates NAT10‐Mediated RNA Acetylation to Modulate DNA Repair and Therapeutic Response in Hepatocellular Carcinoma

MedComm, Volume 7, Issue 9, September 2026.
In hepatocellular carcinoma (HCC) cells exposed to doxorubicin, DUSP12 depletion maintains NAT10 phosphorylation, reducing its acetyltransferase activity, which leads to reduced ac4C RNA acetylation, DNA damage response, and DNA break repair, with consequent tumor sensitization.
Viktor Kalbermatter Boell, Diana Reis Della Corte Guimarães Pacheco, Yuli Thamires Magalhães, Laura Lima Turani, Isabeli Yumi Araújo Osawa, Nicolas Carlos Hoch, Fábio Luís Forti   +6 more
wiley   +1 more source