Results 211 to 220 of about 58,125 (347)

Pharmacokinetics and metabolism of ifosfamide in relation to DNA damage assessed by the COMET assay in children with cancer [PDF]

open access: hybrid, 2005
Iain Willits   +7 more
openalex   +1 more source

Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine

open access: yesPhotochemistry and Photobiology, EarlyView.
6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes   +6 more
wiley   +1 more source

Evaluating nanobiomaterial-induced DNA strand breaks using the alkaline comet assay. [PDF]

open access: yesDrug Deliv Transl Res, 2022
Tutty MA   +4 more
europepmc   +1 more source

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

open access: yesPhotochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan   +3 more
wiley   +1 more source

Cell survival after DNA damage in the comet assay. [PDF]

open access: yesArch Toxicol, 2021
Bankoglu EE, Schuele C, Stopper H.
europepmc   +1 more source

Correction: Evaluating nanobiomaterial-induced DNA strand breaks using the alkaline comet assay. [PDF]

open access: yesDrug Deliv Transl Res, 2022
Tutty MA   +4 more
europepmc   +1 more source

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