Results 271 to 280 of about 1,931,388 (325)

Phloridzin as a Nutraceutical for Cancer Prevention and Therapy: A Comprehensive Review of Its Mechanisms, Bioavailability Challenges and Future Applications

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Phloridzin, a bioactive flavonoid from Malus species, demonstrates diverse therapeutic effects including anticancer, antidiabetic, hepatoprotective, cardioprotective, neuroprotective, and antimicrobial activities. Its anticancer efficacy is mediated through glucose transporter inhibition and modulation of oncogenic signaling pathways.
Praveen Dhyani   +6 more
wiley   +1 more source

Laboratory Practices for the Detection and Characterization of Cryoglobulins and Cryofibrinogen

open access: yesJournal of Clinical Laboratory Analysis, Volume 39, Issue 15, August 2025.
This study shows the importance of carrying out the search for both cryoproteins, cryoglobulins, and cryofibrinogen in cases of strong clinical suspicion of cryoproteinemia, despite their complex but not impossible detection. Use of correct procedures from the pre‐preanalytical phase up to reporting, of alternative methods such as immunotyping and the ...
Teresa Troiano   +5 more
wiley   +1 more source

Differential Effects of Wild Blueberry (Poly)Phenol Metabolites in Modulating Lipid Metabolism and Oxidative Stress in 3T3‐L1 Adipocytes

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Metabolites derived from wild blueberry (poly)phenols, such as syringic (SA), vanillic (VA), and isoferulic acids (IA), can modulate lipid metabolism and oxidative stress markers in mature 3T3‐L1 adipocytes treated with free fatty acids (FFAs; oleic/palmitic acid, 750 µM, 2:1 ratio).
Samuele Venturi   +5 more
wiley   +1 more source

Possible Observations of Plasmaspheric O+

open access: yesJournal of Geophysical Research: Space Physics, Volume 130, Issue 8, August 2025.
Abstract O+ ${\mathrm{O}}^{+}$ is a minor species in the plasmasphere, but its presence significantly alters the dynamics of the magnetosphere system. Many questions remain about the morphology and temporal evolution of plasmaspheric O+ ${\mathrm{O}}^{+}$, in part because it has rarely been observed optically.
Richard M. Tuminello   +5 more
wiley   +1 more source

PAVFCOS: The development of a core outcome set for pouch anal and vaginal fistula

open access: yesColorectal Disease, Volume 27, Issue 8, August 2025.
Abstract Aims The primary aim was to develop a patient‐centred core outcome set (COS) for interventional studies in patients with pouch anal and vaginal fistula (PAVF). Method PAVFCOS was developed using the methodology outlined by the Core Outcome Measures in Effectiveness Trials (COMET). Systematic review and qualitative patient interviews produced a
Lillian Reza   +16 more
wiley   +1 more source

Protective effects of Paeonia suffruticosa callus extract in skin through anti‐inflammation and repair UVB‐induced damage

open access: yesInternational Journal of Cosmetic Science, Volume 47, Issue 4, Page 652-664, August 2025.
Peony callus extract (PCE) is beneficial for skin anti‐ageing and sensitivity induced by UVB radiation, through decreasing the level of inflammatory factors and matrix metalloproteinases. Furthermore, our research indicates that PCE effectively improves the total collagen content in human skin. Abstract Objective The study investigated effects of peony
Yufan Li   +9 more
wiley   +1 more source

From pulp to cementum: 3D visualization of soft and hard dental tissues using different ex vivo nano‐CT contrast‐enhancement techniques

open access: yesInternational Endodontic Journal, Volume 58, Issue 8, Page 1228-1242, August 2025.
Abstract Aim To determine the effect of two contrast‐enhancement strategies in nano‐computed tomography (nano‐CT) imaging on the contrast‐to‐noise ratio (CNR) of various dental tissues, including pulp, dentine and cementum, with the goal of enhancing the visibility of dental soft tissues to a level not yet reported in laboratory nano‐CT imaging ...
Torben Hildebrand   +4 more
wiley   +1 more source

Palladium Complex‐Supported Silica Nanocarriers: Enhancing Therapeutic Efficacy and Reducing Curcumin Toxicity in Breast Cancer

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 15, August 2025.
ABSTRACT Breast cancer (BC) is the most diagnosed tumour worldwide and triple‐negative breast carcinoma (TNBC) stands out among all subtypes due to its high aggressiveness and high mortality rate. Treatments for this subtype are limited to radio‐and chemotherapy due to the lack of specific therapeutic targets.
Lorenzo Rivas‐García   +9 more
wiley   +1 more source

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