Results 101 to 110 of about 2,093,430 (321)

Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley   +1 more source

Ion Probe Measurements of Comet Dust: Investigating Oxygen Isotope Heterogeneity in the Solar System [PDF]

, 2016
The abundances of the stable isotopes of oxygen vary in terrestrial materials in ways that can be explained by mass-dependent fractionation. Refractory inclusions and chondrules in meteorites, however, have oxygen isotopic compositions that are ...
Snead, Christopher Jorge
core  

From patient notes to prognostication: The revolutionary potential of event‐based foundation models in orthopaedics

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract The integration of artificial intelligence (AI)‐equipped tools into electronic health record (EHR) platforms may drive the evolution of orthopaedic diagnosis and decision‐making, leveraging big data to generate precise and context‐aware insights.
Alexander M. Bouterse, James A. Pruneski, Felix C. Oettl, Bálint Zsidai, Umile Giuseppe Longo, Thomas Tischer, Michael T. Hirschmann, Kristian Samuelsson   +7 more
wiley   +1 more source

The Genetic Effects of Aging on Human Mesenchymal Stem Cells through Consecutive Subcultures

پزشکی بالینی ابن سینا, 2013
Introduction & Objective: Stem cells are determined by their unique features. One of them is high proliferation ability and the other is potency of differentiation to various tissues.
Hamid Pourjafari, Bahareh Pourjafari,, Fahimeh Talebzadeh, Alireza Zamani, Seyyed Mohammad Hoseinipanah, Hosein Fazli   +5 more
doaj  

A Sub‐Microsecond Switch Enabling SWIFT 23Na Imaging at 10.5 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To enable sodium SWIFT imaging, which is a zero‐echo time imaging technique, at ultra‐high magnetic fields through the development of custom electronics hardware, and to showcase this capability with in vivo imaging results. Methods The custom hardware developed consists of a high‐speed optical trigger with 10 ns resolution, an in‐bore
Russell L. Lagore, Simon Schmidt, Edward J. Auerbach, Naoharu Kobayashi, Christoph Schildknecht, Steen Moeller, Elnaz Mahmoudi Mahmoudalilou, Štefan Zbýň, Jutta Ellermann, Gregor Adriany, Gregory J. Metzger   +10 more
wiley   +1 more source

Cometary evolution : clues on physical properties from chondritic interplanetary dust particles

, 1997
The degree of diversity or similarity detected in comets depends primarily on the lifetimes of the individual cometary nuclei at the time of analysis. It is inherent in our understanding of cometary orbital dynamics and the seminal model of comet origins
Rietmeijer, Frans J.M., Mackinnon, Ian D.R.   +1 more
core  

Rheological Characterization and Multi‐Regime Viscosity Modeling of Diluted Polyethylene Mixtures

Polymer Engineering &Science, EarlyView.
This study maps the flow behavior of low‐density polyethylene in a recycling solvent from dilute solutions to entangled melts. By integrating time–concentration and time–temperature superposition, and coupling three complementary rheometry methods, a unified semiempirical model accurately predicts steady‐shear viscosity over nine decades of viscosity ...
Johannes Krug, Ernst Georg Viehböck, Alexander Hammer, Ursula Steiner, Christof Murnig, Martin Reichel, Christian Paulik, Gerald Berger‐Weber   +7 more
wiley   +1 more source

Comet C2012 S1 (ISON)s Carbon-rich and Micron-size-dominated Coma Dust

, 2014
Comet C/2012 S1 (ISON) was unique in that it was a dynamically new comet derived from the Nearly Isotropic Oort cloud reservoir of comets with a sun-grazing orbit.
Reach, W., de Pater, I., Yanamadra-Fisher, P., Woodward, C., Russell, R., Gehrz, R., De Buizer, J., Kolokolova, L., Sitko, M., Harker, D., Kelley, M., Kim, D., Wooden, D., Lisse, C.   +13 more
core  

Application of Non‐Isothermal Network Theory With Curved‐Channel Element Characteristics to Predict Melt Conveying in High‐Performance Single‐Screw Extruders

Journal of Polymer Science, EarlyView.
This study presents a fast and accurate calculation tool to predict conveying of polymer melts in single‐screw extruders. Integrating generalized sub‐models into network theory allows to represent the complex screw shapes and material behavior more realistically. Tests on an industrial extruder show close agreement with experiments, outperforming older
Daniel Herzog, Wolfgang Roland, Christian Marschik, Gerald Berger‐Weber   +3 more
wiley   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source