Results 81 to 90 of about 2,093,430 (321)

Noble Gas Planetology and the Xenon Clouds of Uranus

The Planetary Science Journal
Noble gases provide tracers of cosmic provenance that are accessible to a future Uranus atmospheric probe. Argon and krypton are expected to be well mixed on Uranus with respect to H _2 and He, although condensation at the winter pole may be possible ...
Kevin Zahnle
doaj   +1 more source

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

Cytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham, Mihir Relan, Matthew T. Swulius, Andrea K. H. Stavoe   +3 more
wiley   +1 more source

Classification of Subgroups of Solar and Heliospheric Observatory (SOHO) Sungrazing Kreutz Comet Group by the Density-Based Spatial Clustering of Applications with Noise (DBSCAN) Clustering Algorithm

Journal of Astronomy and Space Sciences
Sungrazing comets, known for their proximity to the Sun, are traditionally classified into broad groups like Kreutz, Marsden, Kracht, Meyer, and non-group comets.
Ulkar Karimova, Yu Yi
doaj   +1 more source

Visualizing Specific Tubulin Isotypes and Pathogenic Variants in Cellular Microtubule Arrays

Cytoskeleton, EarlyView.
ABSTRACT Eukaryotic cells depend on dynamic microtubule arrays to execute a wide range of functions vital for life. These microtubule filaments are formed through the polymerization of α/β‐tubulin proteins, which can be generated from numerous tubulin genes, or isotypes.
Sareen Fiaz, Benjamin Powers, Jayne Aiken   +2 more
wiley   +1 more source

Comet Outbursts: Linking Gas Composition Changes to Trigger Mechanisms

, 2023
International audienceDust outbursts observed during the Rosetta mission on comet 67P/Churyumov-Gerasimenko have produced spectacular images described as fireworks in the literature (Vincent et al., 2016).
de Keyser, Johan, Fuselier, Stephen, A., Müller, Daniel, R., Wampfler Susanne, F., Rubin, Martin, Berthelier, Jean-Jacques, Hänni, Nora, Altwegg, Kathrin, Combi, Michael   +8 more
core   +1 more source

Silencing SGO2 by Oxamic Acid Dissociates Glycolysis and BRCA1‐Mediated DNA Repair to Improve the Chemosensitivity of Lung Adenocarcinoma

Exploration, EarlyView.
SGO2 interacts with BRCA1 to inhibit BRCA1 ubiquitination and degradation, thereby promoting BRCA1‐induced DNA damage repair signaling and reducing the chemo sensitivity of LUADa. OA targets glycolysis to disrupt H3K18la‐ and H3K27ac‐mediated chromatin accessibility, repressing SGO2 transcription and subsequently alleviating SGO2‐mediated cancer ...
Xian Lin, Zhidan Hua, Chen Liu, Minxia Yang, Beilei Zhang, Xiaofeng Zhu, Xiao Chen   +6 more
wiley   +1 more source

Computer‐Aided Diagnosis in the Evaluation of Thyroid Nodules: A Study of Intra‐ And Inter‐Rater Reliability and Agreement

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate the intra‐ and inter‐rater reliability of a computer‐aided diagnosis system applied to thyroid nodule assessment. Methods This prospective, single‐center study included 150 thyroid nodules evaluated by two physicians at two time points, 90 days apart.
Leonardo de Souza Piber, Luis Carlos Uta Nakano, Carolina Dutra Queiroz Flumignan, Ronald Luiz Gomes Flumignan   +3 more
wiley   +1 more source

Comet C/1908 R1 (Morehouse) as a C/2016 R2 (PanSTARRS)-like comet

peer reviewedIntroductionComets are pristine relics of the early Solar System, formed from the agglomeration of icy grains and dust particles, offering insights into the evolution of the protosolar nebula (PSN).
Hardy, Pierre, Manfroid, Jean, Robert, Vincent, Jehin, Emmanuel, Noyelles, Benoît., Anderson, Sarah, Rousselot, Philippe   +6 more
core   +1 more source

Primordial Origin of Methane on Eris and Makemake Supported by D/H Ratios

The Astrophysical Journal Letters
Deuterium, a heavy isotope of hydrogen, is a key tracer of the formation of the solar system. Recent James Webb Space Telescope observations have expanded the data set of deuterium-to-hydrogen (D/H) ratios in methane on the KBOs Eris and Makemake ...
Olivier Mousis, Aaron Werlen, Tom Benest Couzinou, Antoine Schneeberger   +3 more
doaj   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source