Results 21 to 30 of about 550,699 (320)
Purpose: This study aims to investigate the use of the neutral comet assay to assess deoxyribonucleic acid (DNA) damage in lymphocytes exposed to high doses of radiation.
Jose Solomon Raj+7 more
doaj +1 more source
Increased DNA damage in blood cells of rat treated with lead as assessed by comet assay [PDF]
A growing body of evidence suggests that oxidative stress is the key player in the pathogenesis of lead-induced toxicity. The present study investigated lead induced oxidative DNA damage, if any in rat blood cells by alkaline comet assay.
Mohammad Arif+5 more
doaj +2 more sources
Beyond the GTP‐cap: Elucidating the molecular mechanisms of microtubule catastrophe
Microtubule dynamics are essential for myriad cellular processes. The switching between microtubule growth and shrinkage is traditionally explained by the loss of a protective “cap” of GTP‐bound tubulin subunits from the growing microtubule end. New research shows that features beyond the nucleotide content at the growing end impact microtubule ...
Veronica J. Farmer, Marija Zanic
wiley +1 more source
The root of a comet tail: Rosetta ion observations at comet 67P/Churyumov–Gerasimenko [PDF]
Context. The first 1000 km of the ion tail of comet 67P/Churyumov–Gerasimenko were explored by the European Rosetta spacecraft, 2.7 au away from the Sun. Aims.
E. Behar+9 more
semanticscholar +1 more source
This study indicated, for the first time, that (±) linalool and its enantiomer, (R)‐(‐) linalool protected PC12 cells against injury induced by oxygen and glucose deprivation/reoxygenation (OGD/R) via the mitigation of oxidative stress and the downregulation of Bax/Bcl‐2, caspase‐3 and caspase‐9, resulting in decreased apoptotic cell death.
Azar Hosseini+5 more
wiley +1 more source
Abstract Introduction Artificial‐intelligence (AI)‐based predictive analytics provide new opportunities to leverage rich sources of continuous data to improve patient care through early warning of the risk of clinical deterioration and improved situational awareness.Part of the success of predictive analytic implementation relies on integration of the ...
Jessica Keim‐Malpass+4 more
wiley +1 more source
Workflow of the experimental study for validating non‐Newtonian co‐extrusion flow models: digital twin of the co‐extrusion process based on symbolic regression models, design of experiments, and error analysis Abstract In the co‐extrusion of plastics, pressure‐throughput behavior, layer distribution, and residence time are crucial parameters, modeling ...
Alexander Hammer+4 more
wiley +1 more source
Comet assay - a sensitive tool for genotoxicity assessment of environmental stress in Mytilus galloprovincialis from the Bulgarian Black Sea coast [PDF]
Assessment of DNA damage is of primary concern when the pollution-related stress in living organisms has to be determined. The reason for this concern comes from the evidence that damages in DNA often lead to mutations which are potential threat for the ...
Bela Vasileva+5 more
doaj +3 more sources
German guideline diverticular disease/diverticulitis
Abstract Diverticulosis and diverticular disease are ranked among the most common gastroenterological diseases and conditions. While for many years diverticulitis was found to be mainly an event occurring in the elder population, more recent work in epidemiology demonstrates increasing frequency in younger subjects.
Wolfgang Kruis+15 more
wiley +1 more source