Results 61 to 70 of about 71,398 (288)
Advanced Science, EarlyView.Under DNA damage, tumor cells rely on efficient DNA repair for survival and therapy resistance. This study has demonstrated that BCKDK localizes to breast cancer cell nuclei, where it binds to and phosphorylates RNF8, thereby blocking ubiquitin‐mediated degradation of RAD51 and enhancing HRR. A selective BCKDK inhibitor synergizes with clinical agents,
Haiying Liu +12 more
wiley +1 more source
AutoComet: A fully automated algorithm to quickly and accurately analyze comet assays
Redox Biology, 2023 DNA damage is a common cellular feature seen in cancer and neurodegenerative disease, but fast and accurate methods for quantifying DNA damage are lacking.
Lise Barbé +6 more
doaj
Probing the Solar Wind Acceleration Region with the Sun--Grazing Comet C/2002 S2 [PDF]
, 2014 Comet C/2002 S2, a member of the Kreutz family of Sungrazing comets, was discovered in white light images of the SOHO/LASCO coronagraph on 2002 September 18 and observed in \hi\, \lya\, emission by the SOHO/UVCS instrument at four different heights as it approached the Sun.
arxiv +1 more source
Tycho Brahe, Abu Mashar, and the comet beyond Venus (ninth century A.D.) [PDF]
Journal for the History of Astronomy 47, 136, 2016, 2016 From his observations of the A.D. 1572 super-nova and the A.D. 1577 comet, Tycho Brahe concluded that such transient celestial objects are outside the Earth's atmosphere, and he quoted the 9th century A.D. Persian astrologer and astronomer Abu Mashar: Dixit Albumasar, Cometa supra Venerem visus fuit, i.e.
arxiv +1 more source
Advanced Science, EarlyView.This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie +8 more
wiley +1 more source
The Slow‐Rotating Nucleus of Comet C/2013 R1 (Lovejoy)
Astronomische Nachrichten, EarlyView.ABSTRACT The close approach of comet C/2013 R1 (Lovejoy) allowed us to conduct an in‐depth study of the morphology of the inner coma. From the measurement of the dust emission structures expanding near the cometary nucleus in November–December 2013, we derived a slow rotation period of 47.8±1.2$$ 47.8\pm 1.2 $$ h.
Federico Manzini +12 more
wiley +1 more source
Comparison Between Different DNA and Conventional
مجله كليه طب الكندي, 2012 Background: The discriminative power of the classical WHO parameters in relation to male fertility is quite low, because they only address few aspects of sperm quality and function.
Estabraq . , A Rasool1 +2 more
doaj
Chemistry &Biodiversity, EarlyView.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
The Astrophysical JournalCometary tails display dynamic behavior attributed to interactions with solar wind structures. Consequently, comet-tail observations can serve as in situ solar wind monitors.
Sarah R. Watson +3 more
doaj +1 more source
Genes and Environment, 2021 Background The in vivo comet assay is used to evaluate the genotoxic potential of compounds by detecting DNA strand breaks in cells isolated from animal tissue.
Haruna Tahara +3 more
doaj +1 more source