Results 61 to 70 of about 53,221 (292)

Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors

Advanced Science, EarlyView.
Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu, WeiYi Cheng, Menghang Yang, Li He, WeiYe Ren, JingQuan Chen, LiTing He, Dandan Bao, Zhihong Zhu, Lixin Wang, Qinghua Yao, Ji‐Gang Piao   +11 more
wiley   +1 more source

“Stars Falling to Earth”—Mental Models of Comets and Meteors

Education Sciences
The present study examines students’ conceptions of comets and meteors using qualitative research methods. A total of 35 semi-structured interviews were conducted with students in grades 7 and 9 in Germany, aiming to gain a richer understanding of how ...
Malte S. Ubben, Fabian Hochhaus, Alexander Pusch   +2 more
doaj   +1 more source

Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

Advanced Science, EarlyView.
We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng, Zhe Lei, Zhehao Zhang, Zhiyue Su, Chonghai Zhang, Huan Yang, Shu Liu, Mengyuan Hu, Yuhong Wang, Lingchuan Guo, Lin Hu, Kai Yang   +11 more
wiley   +1 more source

Point-of-care chest ultrasound in the Neonatal Intensive Care Unit

Journal of Pediatric and Neonatal Individualized Medicine, 2013
Chest ultrasound is a useful diagnostic tool in adult emergency medicine. Echography does not generate a clear image of the lung but is able to generate artifacts that are combined in disease-specific profiles.
Francesco Raimondi, Fiorella Migliaro, Angela Sodano, Gianfranco Vallone, Teresa Ferrara, Sergio Maddaluno, Clara Coppola, Letizia Capasso   +7 more
doaj   +1 more source

Physical Characterization of Main-Belt Comet (248370) 2005 QN173 [PDF]

, 2021
Henry H. Hsieh, Colin Orion Chandler, L. Denneau, A. Fitzsimmons, Nicolas Erasmus, Michael S. P. Kelley, Matthew M. Knight, Tim Lister, J. Pittichová, Scott S. Sheppard, Audrey Thirouin, Chadwick A. Trujillo, Helen Usher, Edward Gomez, Joey Chatelain, Sarah Greenstreet, Tony Angel, R. Miles, P. Roche, Ben Wooding   +19 more
openalex   +1 more source

3D investigation and modeling of the geometric effects on porosity in packed beds

AIChE Journal, EarlyView.
Abstract In porous beds, physical boundaries restrict particle arrangement, leading to inhomogeneous porosity. This paper reports on the porosity profiles that are the result of geometric effects on monodisperse packed beds in cylindrical and cubic arrangements. Special focus is given to the influence of edges and corners in cubic geometries.
Bastian Oldach, Konrad E. R. Boettcher, Alexander S. Sommer‐Behr, Norbert Kockmann   +3 more
wiley   +1 more source

The Formation of Jupiter, the Jovian Early Bombardment and the Delivery of Water to the Asteroid Belt: The Case of (4) Vesta

Life, 2014
The asteroid (4) Vesta, parent body of the Howardite-Eucrite-Diogenite meteorites, is one of the first bodies that formed, mostly from volatile-depleted material, in the Solar System. The Dawn mission recently provided evidence that hydrated material was
Diego Turrini, Vladimir Svetsov
doaj   +1 more source

Crater Observing Bioinspired Rolling Articulator (COBRA)

Advanced Intelligent Systems, EarlyView.
Crater Observing Bio‐inspired Rolling Articulator (COBRA) is a modular, snake‐inspired robot that addresses the mobility challenges of extraterrestrial exploration sites such as Shackleton Crater. Incorporating snake‐like gaits and tumbling locomotion, COBRA navigates both uneven surfaces and steep crater walls.
Adarsh Salagame, Henry Noyes, Eric Sihite, Arash Kalantari, Alireza Ramezani   +4 more
wiley   +1 more source

Low‐Level Mosaicism in Tuberous Sclerosis Complex (TSC): Diagnostic and Clinical Implications From Two Novel Cases and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Mosaicism is relatively common in Tuberous Sclerosis Complex (TSC) but can be difficult to detect using routine diagnostic tests, particularly when the variant allele frequency (VAF) is low. We describe two cases of mosaic TSC diagnosed using an ultra‐deep sequencing approach in multiple tissues and review the literature about this topic in ...
Irene Ambrosetti, Carlotta Pia Cristalli, Francesca Montanari, Luca Caramanna, Francesco Modestino, Irene Capelli, Valeria Aiello, Sarah Lerario, Cecilia Evangelisti, Iria Neri, Eugenio Brunocilla, Cesare Rossi, Marco Seri, Daniela Turchetti, Giovanni Innella   +14 more
wiley   +1 more source

Search for the True Parent Body of the Phoenicid Meteor Shower

The Astronomical Journal
In 2024, Ďurišová et al. found that the meteor shower Phoenicids, IAU No. 254, code PHO, can originate in the nuclei of three comets, 46P/Wirtanen, 104P/Kowal 2, and 289P/Blanpain.
Martina Kováčová, Luboš Neslušan, Dušan Tomko   +2 more
doaj   +1 more source