Results 61 to 70 of about 35,890 (293)
Gut and Liver, 2016 Background/AimsThe covered self-expandable metal stent (CMS) was developed to prevent tumor ingrowth-induced stent occlusion during the treatment of malignant biliary obstruction.
Jin-Seok Park +5 more
doaj +1 more source
Advanced Science, EarlyView.The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo +14 more
wiley +1 more source
Duodenopancreatectomias: análise de 39 pacientes
Revista do Colégio Brasileiro de CirurgiõesOBJETIVO: Pretendemos neste estudo analisar 39 pacientes submetidos à duodenopancreatectomia. MÉTODO: No período de julho de 1998 a março de 2004, trinta e nove pacientes foram submetidos a duodenopancreatectomia no Hospital Universitário da Universidade
Orlando Jorge Martins Torres +5 more
doaj +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Innovations in macroscopic evaluation of pancreatic specimens and radiologic correlation
European Journal of Radiology Open, 2016 The purpose of this study was to evaluate the feasibility of a novel dissection technique of surgical specimens in different cases of pancreatic tumors and provide a radiologic pathologic correlation.
Charikleia Triantopoulou +3 more
doaj +1 more source
A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel. [PDF]
, 2019 Pexidartinib (PLX3397) is a small molecule tyrosine kinase and colony-stimulating factor-1 inhibitor with FDA breakthrough therapy designation for tenosynovial giant-cell tumor, and currently under study in several other tumor types, including breast ...
Chien, A Jo +5 more
core
Theoretical investigation of transgastric and intraductal approaches for ultrasound-based thermal therapy of the pancreas. [PDF]
, 2017 BackgroundThe goal of this study was to theoretically investigate the feasibility of intraductal and transgastric approaches to ultrasound-based thermal therapy of pancreatic tumors, and to evaluate possible treatment strategies.MethodsThis study ...
Adams, Matthew S +4 more
core +1 more source
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association), 2011 症例は78歳，女性．平成15年4月，膵頭部に3cm大の腫瘤像を認め分枝型IPMNと診断され，以後外来で経過観察されていた．平成18年5月，下腹部痛，微熱が出現し，当院に入院となった．CT上，腫瘍の増大傾向を認め，嚢胞内に新たに充実性病変を認めた．ERCP検査にて主膵管は数珠状に拡張し，嚢胞内に充実性成分と思われる欠損像を認めた．膵管内超音波検査にて嚢胞内に充実性の腫瘤を認め，生検ではIPMN with moderate dysplasiaであった．ERCP5日後，閉塞性黄疸を認めたためERBDチューブを留置した．減黄後，膵頭十二指腸切除術を施行した．術後の標本検索では，嚢胞と総胆管に直径約1cmの瘻孔を認めた．病理検査上，瘻孔部に腫瘍細胞は認めなかった ...
Naoki AOMATSU +5 more
openaire +2 more sources
A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection
Advanced Science, EarlyView.A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang +8 more
wiley +1 more source
Poorly Cohesive Carcinoma of Common Bile Duct: A Rare Histological Type of Cholangiocarcinoma
Clinical Medicine Insights: Case ReportsBiliary tract carcinomas (BTC) are malignant epithelial neoplasms subdivided anatomically into: gallbladder carcinomas and carcinomas of the bile duct or cholangiocarcinomas (CCA); including intrahepatic, hilar/perihilar, and distal CCA.
Derqaoui Sabrine +6 more
doaj +1 more source