Results 71 to 80 of about 4,973,845 (291)

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Poorly Cohesive Carcinoma of Common Bile Duct: A Rare Histological Type of Cholangiocarcinoma

Clinical Medicine Insights: Case Reports
Biliary tract carcinomas (BTC) are malignant epithelial neoplasms subdivided anatomically into: gallbladder carcinomas and carcinomas of the bile duct or cholangiocarcinomas (CCA); including intrahepatic, hilar/perihilar, and distal CCA.
Derqaoui Sabrine, Hamid Mohamed, Ahmed jahid, Kaoutar Znati, Fouad Zouaidia, Settaf Abdellatif, Bernoussi Zakiya   +6 more
doaj   +1 more source

Percutaneous Transabdominal Metallic Stent Placement for Palliation of Afferent Loop Syndrome: A Case Report

대한영상의학회지, 2019
The authors report a successful outcome after percutaneous transabdominal placement of a self-expandable metallic stent in a patient who had afferent loop syndrome caused by recurrent common bile duct adenocarcinoma. Enhanced abdominal CT showed marked
Kun Yung Kim, Young Min Han, Eun Ha Jung, Gong Yong Jin, Kum Ju Chae, Kang Ji Lee   +5 more
doaj   +1 more source

A CASE OF INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM OF THE PANCREAS WHICH PENETRATED THE COMMON BILE DUCT WITH OBSTRUCTIVE JAUNDICE

Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association), 2011
症例は78歳，女性．平成15年4月，膵頭部に3cm大の腫瘤像を認め分枝型IPMNと診断され，以後外来で経過観察されていた．平成18年5月，下腹部痛，微熱が出現し，当院に入院となった．CT上，腫瘍の増大傾向を認め，嚢胞内に新たに充実性病変を認めた．ERCP検査にて主膵管は数珠状に拡張し，嚢胞内に充実性成分と思われる欠損像を認めた．膵管内超音波検査にて嚢胞内に充実性の腫瘤を認め，生検ではIPMN with moderate dysplasiaであった．ERCP5日後，閉塞性黄疸を認めたためERBDチューブを留置した．減黄後，膵頭十二指腸切除術を施行した．術後の標本検索では，嚢胞と総胆管に直径約1cmの瘻孔を認めた．病理検査上，瘻孔部に腫瘍細胞は認めなかった ...
AOMATSU, Naoki, YAMADA, Nobuya, AMANO, Ryosuke, NAKATA, Bunzo, OHIRA, Masaichi, HIRAKAWA, Kosei   +5 more
openaire   +2 more sources

Characteristics of bile duct carcinoma with superficial extension in the epithelium. [PDF]

, 2009
BACKGROUND: Longitudinal tumor extension from the main tumor involves intramural or superficial spread along the bile duct, which influences surgical curability. Identifying the range of superficial extension is difficult by preoperative imaging.
Nanashima, Atsushi, Takeshita, Hiroaki, Sawai, Terumitsu, Nagayasu, Takeshi, Abo, Takafumi, Tobinaga, Syuuichi, Hidaka, Shigekazu, Fukuoka, Hidetoshi, Sumida, Yorihisa   +8 more
core   +1 more source

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

Advanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok, Laura Činč Ćurić, Jernej Vajda, Silvia Schauer, Martin Wagner, Rudolf Stauber, Carolin Lackner, Karl Kashofer, Markus Plass, Giovanny Rodriguez Blanco, Ian R. Wanless, Uroš Maver, Katrin Panzitt, Boštjan Vihar   +13 more
wiley   +1 more source

Papillary neoplasias of the biliary tract

Revista do Colégio Brasileiro de Cirurgiões
The authors conducted a revisional study of intraepithelial papillary lesions of the bile ducts, characterized by being a kind of rare, intraductal growing cholangiocarcinoma. Articles published in the last 10 years were reviewed.
Vivian Resende, João Paulo Lemos da Silveira Santos, Rodrigo Vieira Gomes, Paula Vieira Teixeira Vidigal, Moisés Salgado Pedrosa   +4 more
doaj   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Pancreatic Polypeptide-Secreting Tumour of the Proximal Pancreas (PPoma)—Ultra Rare Pancreatic Tumour: Clinically Malign, Histologically Benign

Medicina, 2019
Background and objectives: Here we report a rare case of a pancreatic polypeptide-secreting tumour (PPoma) discovered by accident during an autopsy. These PPomas occur in less than 2% of all pancreatic neoplasms and are almost exclusively silent, i.e ...
Ivan Ilić, Vuka Katić, Pavle Randjelović, Nikola Stojanović, Aleksandra Antovic, Ratko Ilić   +5 more
doaj   +1 more source

Clinical utility of linear endosonography in patients with unexplained biliary dilatation and negative MRCP, with predictors for detection of neoplastic lesions

Egyptian Liver Journal, 2022
Background and study aims Unexplained biliary dilatation (UBD) frequently represents a diagnostic dilemma. Linear endosonography (EUS), with its close proximity to the pancreaticobiliary system and the ability for tissue acquisition, could have a role in
Hassan Atalla, Ayman Menessy, Hazem Hakim, Hideyuki Shiomi, Yuzo Kodama, Elsayed Ghoneem   +5 more
doaj   +1 more source