Results 61 to 70 of about 2,477,472 (306)
Numerically Predicted Buckling Design Criteria for Elliptical Common Bulkhead Structures
International Journal of Aerospace EngineeringA common bulkhead (CB) structure that separates the oxidizer and fuel regions without an interstage single tank reduces the weight of the propellant tanks of launch systems.
Gi-Seop Kim +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Sensors, 2010 The paper discusses the security issues of intelligent sensors that are able to measure and process data and communicate with other information technology (IT) devices or systems. Such sensors are often used in high risk applications.
Andrzej Bialas
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Vulnerability Assessment of Sensor Systems
Sensors, 2019 There are more and more applications of sensors in today’s world. Moreover, sensor systems are getting more complex and they are used for many high-risk security-critical purposes.
Andrzej Bialas
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Optimal Predictive Criteria for Common Bile Duct Stones: The Search Continues [PDF]
Clinical Endoscopy, 2021 Yun Nah Lee, Jong Ho Moon
doaj +1 more source
Assurance Considerations for a Highly Robust TOE [PDF]
, 2007 The U.S. Government Protection Profile for Separation Kernels in Environments Requiring High Robustness (SKPP) is undergoing evaluation. During its authoring process, new extended functional and assurance requirements were introduced to resolve assurance
Levin, Timothy E. +3 more
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