Results 71 to 80 of about 2,477,472 (306)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Can South Asia Adopt a Common Currency? [PDF]
The paper examines if the seven South Asian countries satisfy the criteria to form an optimal currency area. The empirical part of the paper reveals some positive attributes (such as the existence of positive shocks for major economies like India ...
Sweta C. Saxena
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Beveiligingsevaluaties met de Common Criteria
, 1996 Na de publicatie in 1985 van de Amerikaanse Trusted Computer Systems Evaluation Criteria (TCSEC), die een aantal normen gaf voor beveiligingsevaluaties, verschenen in binnen- en buitenland diverse afgeleiden. De laatste afstammeling is de Common Criteria,
Franken, P.W.M.
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Integrating multiple criteria decision analysis into participatory forest planning [PDF]
, 2010 Following the development of sustainable forest management, the focus of forest planning has shifted from being exclusively concerned with timber production to encompassing other benefits of forests as well, e.g. biodiversity and recreation.
Nordström, Eva-Maria
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Development of Diagnostic Criteria for Common Warts (Verrucae Vulgaris)
, 1997 Background: Warts are common skin conditions. In most instances, their diagnosis by medical practitioners is a subjective or intuitive decision. Objective: To develop and assess a minimum set of diagnostic criteria for diagnosis of common warts. Methods:
Monique Kilkenny +3 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
The Shrinking Endogeneity of Optimum Currency Areas Criteria: Evidence from the European Monetary Union – A Beta Regression Approach. [PDF]
The endogeneity of optimum currency areas criteria has been widely studied since Frankel and Rose (1998) seminal paper. Literature normally suggests that there is a positive relationship between trade and business cycles correlation.
José Passos +2 more
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