Results 81 to 90 of about 2,477,472 (306)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Comparing Semivariance and Calculated Beta on Basis of it to the Variance and Common Beta [PDF]
تحقیقات مالی, 2009 In this article the researcher, comparing Semivariance and calculated Beta on basis of it to the variance and common Beta, has tried to see whether Downside Beta criteria (Semivariance and calculated Beta on basis of it) have any preference over the ...
Reza tehrani, Moslem Peymany
doaj
A Problem-Oriented Approach to Common Criteria Certification [PDF]
, 2002 There is an increasing demand to certify the security of systems according to the Common Criteria (CC). The CC distinguish several evaluation assurance levels (EALs), level EAL7 being the highest and requiring the application of formal techniques. We present a method for requirements engineering and (semi-formal and formal) modeling of systems to be ...
Rottke, Thomas +3 more
openaire +1 more source
A Proposal on Security Case Based on Common Criteria [PDF]
, 2013 It is important to assure the security of systems in the course of development. However, lack of requirements analysis method to integrate security functional requirements analysis and validation in upper process often gives a crucial influence to the system dependability.
Shuichiro Yamamoto +2 more
openaire +2 more sources
Common Criteria IT Security Standard in Product Development Process [PDF]
, 2010 Tietoturvallisuutta tarvitaan informaatioteknologian (IT) tuotteissa ja järjestelmissä. Yksi tapa varmistaa tuotteiden turvallisuus on käyttää IT -turvallisuusstandardeja.
Tulensalo, Maria
core
Inclusion and exclusion criteria for publicly-funded homebirth in Australia: A scoping review
, 2021 Background There are fifteen publicly-funded homebirth programs currently operating in Australia. Suitability for these programs is determined by a series of inclusion and exclusion criteria.
Blums, Tija +2 more
core +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Educational Process of Interns in Obstetrics & Gynecology Department at Zahedan University of Medical Sciences in 2002 [PDF]
مجله ایرانی آموزش در علوم پزشکی, 2003 Introduction. Investigating educational situations of interns in different departments is one of the objectives of educational planning in order to prevent a low quality education and provide some solution for that. This study was done to investigate the
Masoud Roudbari +2 more
doaj