Results 11 to 20 of about 4,530 (166)

Clinical and Immunological Spectrum of Common Variable Immunodeficiency (CVID)

Iranian Journal of Allergy, Asthma and Immunology, 2004
We have analysed data from 150 patients initially classified as having CVID. About 10% had laboratory abnormalities suggesting known single gene disorders (eg: hyper-IgM syndrome), and in a few a genetic defect has been confirmed.
Anthony David B. Webster
doaj   +2 more sources

Patients With Common Variable Immunodeficiency (CVID) Show Higher Gut Bacterial Diversity and Levels of Low-Abundance Genes Than the Healthy Housemates [PDF]

Frontiers in Immunology, 2021
Tomáš Freiberger, Juraj Bosak, Jiří Litzman   +2 more
exaly   +2 more sources

Investigating serum free light chains in patients with common variable immunodeficiency disorder in compare with other immunodeficiency diseases [PDF]

Scientific Reports
Serum free light chains (sFLCs) have recently been introduced as a diagnostic biomarker in common variable immunodeficiency (CVID) patients. Most patients with CVID have undetectable or lower levels of sFLCs compared to people with other types of immune ...
Mohammad Hassan Bemanian, Majid Khoshmirsafa, Mina Ahmadi, Mohamad Nabavi, Saba Arshi, Zahra Chavoshzadeh, Sima Shokri, Morteza Fallahpour, Negin Jafariaghdam, Fatemeh Afrashteh, Samane Asefi, Mehrnaz Mesdaghi, Samin Sharafian   +12 more
doaj   +2 more sources

The Scope and Impact of Viral Infections in Common Variable Immunodeficiency (CVID) and CVID-like Disorders: A Literature Review [PDF]

Journal of Clinical Medicine
Siniša Savic, Mark Kačar, Adam Al-Hakim   +2 more
exaly   +2 more sources

Common variable immunodeficiency (CVID) presenting with malabsorption due to giardiasis

The Turkish Journal of Gastroenterology, 2005
Common variable immunodeficiency is characterized with B-cell and T-cell dysfunction and hypogammaglobulinemia. Recurrent bacterial infections, such as otitis media, chronic sinusitis and recurrent pneumonia due to diminished immunoglobulin (Ig) levels and impaired antibody production are frequently observed in common variable immunodeficiency.
Kevser ONBAŞI, Fulya GÜNŞAR, Aytül Z. SİN, Ömür ARDENİZ, Ali KOKULUDAĞ, Filiz SEBİK   +5 more
doaj   +3 more sources

Severe diabetic ketoacidosis and autoimmune pancreatitis with SIRS in an adolescent with LRBA deficiency – A rare complication of a common primary immunodeficiency disease

Journal of Family Medicine and Primary Care, 2022
Common variable immunodeficiency is the most common primary immunodeficiency disorder. Lipopolysaccharide (LPS)-responsive beige-like anchor protein (LRBA) deficiency is categorized as a common variable immunodeficiency associated with autoimmune ...
Divya Ravindran, Rajavel Sagul Ramanuja Mugunthan, Tarikere Krishnamurthy Shruthi, Dhaarani Jayaraman   +3 more
doaj   +1 more source

Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses

Nature Communications, 2022
Common variable immunodeficiency (CVID) is the most prevalent primary immunodeficiency. Here the authors perform single-cell omics analyses in CVID-discordant monozygotic twins and show epigenetic and transcriptional alterations associated with ...
Javier Rodríguez-Ubreva, Anna Arutyunyan, Marc Jan Bonder, Lucía Del Pino-Molina, Stephen J. Clark, Carlos de la Calle-Fabregat, Luz Garcia-Alonso, Louis-François Handfield, Laura Ciudad, Eduardo Andrés-León, Felix Krueger, Francesc Català-Moll, Virginia C. Rodríguez-Cortez, Krzysztof Polanski, Lira Mamanova, Stijn van Dongen, Vladimir Yu. Kiselev, María T. Martínez-Saavedra, Holger Heyn, Javier Martín, Klaus Warnatz, Eduardo López-Granados, Carlos Rodríguez-Gallego, Oliver Stegle, Gavin Kelsey, Roser Vento-Tormo, Esteban Ballestar   +26 more
doaj   +1 more source

Recent advances in elucidating the genetics of common variable immunodeficiency

Genes and Diseases, 2020
Common variable immunodeficiency disorders (CVID), a heterogeneous group of inborn errors of immunity, is the most common symptomatic primary immunodeficiency disorder. Patients with CVID have highly variable clinical presentation.
Vaishali Aggarwal, Aaqib Zaffar Banday, Ankur Kumar Jindal, Jhumki Das, Amit Rawat   +4 more
doaj   +1 more source

Fatal epistaxis in a case of common variable immunodeficiency: A case report and review of the literature

Clinical Case Reports, 2022
Common variable immunodeficiency (CVID) is a primary immunodeficiency disease. We present a case of a patient with CVID complicated by rhinosinusitis with granulomatous inflammation.
Lucy Barber, Anthony Jordan, Richard Douglas   +2 more
doaj   +1 more source

Case Report: Infantile-Onset Fulminant Type 1 Diabetes Mellitus Caused by Novel Compound Heterozygous LRBA Variants

Frontiers in Immunology, 2021
Lipopolysaccharide-responsive beige-like anchor (LRBA) deficiency is a subtype of common variable immune deficiency (CVID). Numerous case reports and cohort studies have described a broad spectrum of clinical manifestations and variable disease ...
Eriko Totsune, Tomohiro Nakano, Kunihiko Moriya, Daichi Sato, Dai Suzuki, Akinobu Miura, Saori Katayama, Hidetaka Niizuma, Junko Kanno, Menno C. van Zelm, Menno C. van Zelm, Kohsuke Imai, Hirokazu Kanegane, Yoji Sasahara, Shigeo Kure   +14 more
doaj   +1 more source