Results 71 to 80 of about 520,835 (347)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Clinical characteristics and risk factors of Hepatitis E virus infection in Zhejiang Province: a multicenter case–control study

Frontiers in Public Health
IntroductionHepatitis E (HE), caused by the Hepatitis E virus (HEV), is a significant cause of acute viral hepatitis globally and a major public health concern, particularly in specific high-prevalence areas in China, which have diverse transmission ...
Yijuan Chen, Jian Gao, Wanwan Sun, Weiping Zhu, Pingping Wang, Xiaobin Ren, Yumeng Wu, Jianli Zhang, Ziping Miao   +8 more
doaj   +1 more source

The methodology for assessing smoking-attributed mortality based on All Causes of Death Surveillance in Tianjin, China, 2010–2015

Tobacco Induced Diseases, 2020
Introduction The All Causes of Death Surveillance (ACDS) system was used to measure smoking-attributed mortality by inserting questions on smoking on death certificates.
Wei Li*, Dezheng Wang*, Hui Zhang, Ying Zhang, Wenlong Zheng, Xiaodan Xue, Wenda Shen, Freddy Sitas, Guohong Jiang   +8 more
doaj   +1 more source

Communicable disease control in Afghanistan

Global Public Health, 2013
Among public health challenges in Afghanistan, communicable diseases still predominate because the epidemiologic transition to chronic disease has not yet occurred. Afghanistan's 10-year journey to improve its response to communicable disease is reflected in varying degrees of progress and innovation, all while long-standing conflict and geographic ...
Mohammad S, Ikram, Clydette L, Powell, Rashida A, Bano, Arshad D, Quddus, Syad K, Shah, Ellyn L, Ogden, Waqar R, Butt, Mohd Arshil, Moideen   +7 more
openaire   +2 more sources

STD Services Delivery Arrangements in Georgia County Health Departments [PDF]

, 2017
Background: Uniformity, standardization, and evidence-based public health practice are needed to improve the efficiency and quality of services in local health departments (LHDs).
Angie Peden, Bill Livingood, Gulzar H. Shah, Karmen S. Williams   +3 more
core   +2 more sources

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Characteristics and timeliness of intervention in 47 school-based enterovirus outbreaks in Zhejiang Province, China

Frontiers in Public Health
BackgroundHand, foot, and mouth disease (HFMD) and herpangina (HA) are common infectious diseases in children that can frequently lead to outbreaks. Analyzing the characteristics of school-based outbreaks and evaluating the timeliness of prevention and ...
Yijuan Chen, Wanwan Sun, Xiaobin Ren, Xiaomin Gu, Kai Song, Pingping Wang, Yanli Cao, Jianmin Jiang, Jianmin Jiang, Ziping Miao, Ziping Miao   +10 more
doaj   +1 more source

The Other \u27VD\u27: The Educational Campaign to Reduce Venereal Disease Rate During World War II [PDF]

, 2016
Venereal disease was a major contributor to lost man days in World War I so the government attempted to implement an educational campaign beginning in 1918.
Gaiser, Madeleine L.
core   +1 more source

Use of m-Health Technology for Preventive Interventions to Tackle Cardiometabolic Conditions and Other Non-Communicable Diseases in Latin America- Challenges and Opportunities [PDF]

, 2016
In Latin America, cardiovascular disease (CVD) mortality rates will increase by an estimated 145% from 1990 to 2020. Several challenges related to social strains, inadequate public health infrastructure, and underfinanced healthcare systems make ...
Beratarrechea, Andrea Gabriela, Diez Canseco, Francisco, Irazola, Vilma, Miranda, Jaime, Ramirez Zea, Manuel, Rubinstein, Adolfo Luis   +5 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source