Results 41 to 50 of about 419,828 (359)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mathematical modelling of community acquired antibiotic resistant infections

Informatics in Medicine Unlocked
Antibiotic usage in hospitals is considered the major driver of the emergence of antibiotic resistance where selection of multiply resistant strains is most common. However, massive antibiotic consumption occurs in the community. We formulate and analyse
Josiah Mushanyu
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Extended-Spectrum β-Lactamase and Carbapenemase-Producing Gram-Negative Bacteria and Associated Factors Among Patients Suspected of Community and Hospital-Acquired Urinary Tract Infections at Ayder Comprehensive Specialized Hospital, Tigrai, Ethiopia

Infection and Drug Resistance, 2023
Mulu Gebretsadik Gebremedhin,1 Yemane Weldu,2 Atsebaha Gebrekidan Kahsay,2 Gebrecherkos Teame,3 Kelemework Adane4 1Ayder Comprehensive Specialized Hospital, Mekelle University, Mekelle, Tigrai, Ethiopia; 2Department of Medical Microbiology and Immunology,
Gebremedhin MG, Weldu Y, Kahsay AG, Teame G, Adane K   +4 more
doaj  

Neutrophil-to-lymphocyte ratio: a potential supportive marker for elderly community-acquired bloodstream infections—a retrospective study [PDF]

PeerJ
Background Exploring the value of the neutrophil/lymphocyte ratio (NLR) as a potential supportive marker in community-acquired bloodstream infection in elderly patients.
Peijuan Li, Jiulin Zhang, Kun Chen, Qianqian Pei, Mengxi Ding, Chunmei Wang   +5 more
doaj   +2 more sources

Diferenças no Perfil Microbiológico entre as Infecções da Comunidade, Associadas a Cuidados de Saúde e Nosocomiais [PDF]

, 2013
INTRODUCTION: Microbiological profiles were analysed and compared for intra-abdominal, urinary, respiratory and bloodstream infections according to place of acquisition: community-acquired, with a separate analysis of healthcare-associated, and hospital-
Aragâo, I, Cardoso, T., Costa-Pereira, A., Ribeiro, O., Sarmento, A.   +4 more
core  

Microbiology of healthcare-associated infections and the definition accuracy to predict infection by potentially drug resistant pathogens: a systematic review [PDF]

, 2015
Background: Healthcare-associated infections (HCAI) represent up to 50 % of all infections among patients admitted from the community. The current review intends to provide a systematic review on the microbiological profile involved in HCAI, to compare ...
Almeida, Mònica, Aragão, Irene, Azevedo, Luís, Cardoso, Teresa, Carratalà, Jordi, Costa-Pereira, Altamiro, Sarmento, António   +6 more
core   +4 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Aetiology of community-acquired neonatal sepsis in low and middle income countries [PDF]

, 2011
99% of the approximate 1 million annual neonatal deaths from life-threatening invasive bacterial infections occur in developing countries, at least 50% of which are from home births or community settings.
Ahmad, Aziez, Campbell, Harry, Jawad, Issrah, Lukšić, Ivana, Nair, Harish, Rudan, Igor, Theodoratou, Evropi, Waters, Donald, Zaidi, Anita K M, Zgaga, Lina   +9 more
core   +1 more source

The potential negative impact of antibiotic pack on antibiotic stewardship in primary care in Switzerland: a modelling study. [PDF]

, 2020
BACKGROUND: In Switzerland, oral antibiotics are dispensed in packs rather than by exact pill-count. We investigated whether available packs support compliance with recommended primary care treatment regimens for common infections in children and adults.
Berger, C, Bielicki, JA, Bornand, D, Füri, J, Huttner, B, Widmer, A   +5 more
core   +3 more sources