Results 71 to 80 of about 814,123 (319)
Successfully Building a Virtual Community: What Are We Learning as We Create the Future of the IP Community? [PDF]
, 2003 This paper provides a brief summary of the activities, successes and challenges faced within the IP Community after the September 2002 community-wide Appreciative Inquiry Summit.
Bright, David
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Geosciences for Elementary Educators: A Course Assessment [PDF]
, 2003 Geosciences for Elementary Educators engages future elementary teachers in a hands-on investigation of topics aligned with the third and fifth grade Earth/Space Science and Scientific Inquiry benchmarks of the Oregon Content Standards.
Burmester, D. +2 more
core +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Community of Inquiry Framework and Learning Outcomes
, 2011 First described by Garrison, Anderson, and Archer (2000), the Community of Inquiry (CoI) framework suggests social presence, teaching presence, and cognitive presence are essential elements to foster successful educational experiences in computer-mediated higher education distance learning environments.
openaire +2 more sources
How reliable and consistent is our learning community of inquiry? Psychometric qualities of the community inquiry survey instrument applied to a sample of higher education portuguese students [PDF]
, 2011 The purpose of this study was to report on the adaptation and empirical evidence to support the validation of the Community of Inquiry Survey Instrument based on the Community of Inquiry (CoI) framework (Garrison, Anderson & Archer, 2000).
Almeida, Ana Cristina +1 more
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Research on College English Blended Teaching Design and Strategy under the Framework of Inquiry Community Theory [PDF]
, 2021 Xiaolu Wu, Wenbo Zhao
openalex +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source