Results 91 to 100 of about 173,833,388 (285)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Online kinesiology: using the community of inquiry framework to enhance students’ learning experiences [PDF]

open access: yes, 2019
The purpose of this study was to examine the effects of the Community of Inquiry (CoI) framework on students’ perspectives of an online Kinesiology course.
Bukhin, Cassandra E.   +1 more
core  

A response to the review of the community of inquiry framework

open access: yes, 2009
The Community of Inquiry (CoI) framework has become a prominent model of teaching and learning in online and blended learning environments. Considerable research has been conducted which employs the framework with promising results, resulting in wide use
Garrison, R   +6 more
core   +3 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Historical inquiry in the middle years [PDF]

open access: yes, 2012
Australia has a new Curriculum and in 2013 the Australian Curriculum: History is scheduled for implementation. Implementation of the new Curriculum for History, may mean additional pressure for teachers implementing historical inquiry as a framework for ...
Salton, Yvonne, McIntyre, Jennifer
core  

Students’ perceptions on IWB through the lens of the community of inquiry framework

open access: yesSouth African Journal of Education, 2015
Interactive whiteboards (IWBs) are being utilised at a rapidly increasing rate, especially in distance education (DE). As a medium of instruction they allow the presenter to simultaneously interact with numerous students at different centres across the country. This study is unique in the sense that a collaborative learning community is created between
openaire   +5 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

The community of inquiry framework for virtual team-to-team debriefings during interprofessional trauma simulations. [PDF]

open access: yesGlobal Surg Educ, 2022
Dickinson KJ   +7 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

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