Results 51 to 60 of about 228,337 (250)

Development and Validation of a Measurement Scale for the Professionalization of University Students in Health Sciences

open access: yesMesure et Évaluation en Éducation, 2022
This article presents the results of a study aimed at constructing and validating a scale for measuring the professionalization of health sciences students.
Marilou Bélisle   +7 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Successful Management of Acquired von Willebrand Syndrome Associated with Monoclonal Gammopathy of Undetermined Significance After Sotorasib Treatment in a Patient with Non-Small-Cell Lung Carcinoma

open access: yesHematology Reports
Background: This case report investigates the effects of sotorasib treatment in a patient with acquired von Willebrand syndrome (AVWS) associated with monoclonal gammopathy of undetermined significance (MGUS), who subsequently developed non-small-cell ...
Mélissa Julien   +5 more
doaj   +1 more source

Les normes régissant le transfert et l'exercice du pouvoir régional au Maroc

open access: yesRevista Internacional de Pensamiento Político, 2022
La clarification des compétences régionales est une opération juridique qui ne peut, évidemment, se limiter dans l’énumération d’un ensemble de matières ou de principes qui dirigent leur répartition. Il est fondamental d’optimiser les conditions de leur
Mohamed Mezgheri
doaj  

Politique de gestion des ressources humaines - règlement n°18 [PDF]

open access: yes, 1998
Politique de gestion des ressources humaines - règlement numéro 18 ; ; Annexe A : Répertoire des habiletés professionnelles et des comportements observables ; Annexe B : Personnel professionnel non-enseignant - Profil des compétences attendues ...

core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Maîtrise des déterminants par les apprenants de 5ème AP et de 4èmeAM.

open access: yesRevue des Sciences Humaines, 2020
Cette recherche s’inscrit dans le cadre de la didactique du FLE, et plus précisément dans l’enseignement de la grammaire. Dans ce modeste travail, nous nous sommes intéressée à l’évaluation des compétences des apprenants du primaire et du collège au ...
Louiza Louiza
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

L’échafaudage lors de la supervision en milieu professionnel : étude des modalités et un modèle

open access: yesMesure et Évaluation en Éducation, 2009
L’échafaudage mis en place en milieu de travail est un aspect important d’une formation professionnelle. Ici, l’hypothèse qu’un superviseur en soins infirmiers a offert un échafaudage adaptatif, explicite et efficace est investiguée et un modèle est ...
Léon Harvey
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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