Results 41 to 50 of about 69,778 (247)
We introduce a new covering property, defined in terms of order types of sequences of open sets, rather than in terms of cardinalities. The most general form depends on two ordinal parameters. Ordinal compactness turns out to be a much more varied notion than cardinal compactness.
openaire +5 more sources
6 pages 5 figures, version accepted for publication in PRD.
Murayama, Hitoshi +3 more
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
One of the main advantages of warm mix asphalt (WMA) used as an alternative to conventional hot mix asphalt (HMA), is to reduce mixing and compaction temperatures. This laboratory study was conducted with the aim of determining physical properties of WMA
Amir Kavussi, Leila Hashemian
doaj +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Assurance of asphalt pavement layer compaction, expressed by air voids ratio between field and laboratory bulk density, is one of the main criteria of the asphalt pavement durability. Thus, destructive measures should be applied, and many asphalt samples
Andrius Baltrušaitis +2 more
doaj +1 more source
A nursing licensure compact is an agreement between two or more states that the licensing of a nurse in one place will be valid in the other. This is especially critical for the occupational health nurse, who may practice in more than one state.
openaire +2 more sources
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Introduction. The authors present the numerical calculation of the hydro-liquid leakage throughthe radial clearance of the “piston - hydraulic cylinder” conjugate node on the basis of determiningthe sealing elements’ resource of the tower crane hydraulic
D. A. Potakhov, Ya. S. Vatulin
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

