Results 71 to 80 of about 524,833 (330)

Fabrication of Highly Compacted Green Body Using Multi-Sized Al Powder under a Centrifugal Force

open access: yesJournal of Manufacturing and Materials Processing, 2022
This study investigates the application of centrifugal force for the compaction of metal powder. Previous studies using the centrifugal force for manufacturing the green bodies were focused on fine powders with narrow particle size distribution or binary
Bakytzhan Sariyev   +4 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Along the Process Chain to Probiotic Tablets: Evaluation of Mechanical Impacts on Microbial Viability

open access: yesPharmaceutics, 2020
Today, probiotics are predominantly used in liquid or semi-solid functionalized foods, showing a rapid loss of cell viability. Due to the increasing spread of antibiotic resistance, probiotics are promising in pharmaceutical development because of their ...
Karl Vorländer   +3 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Nonlinear Viscoelastic Compaction in Sedimentary Basins [PDF]

open access: yes, 2010
In the mathematical modelling of sediment compaction and porous media flow, the rheological behaviour of sediments is typically modelled in terms of a nonlinear relationship between effective pressure $p_e$ and porosity $\phi$, that is $p_e=p_e(\phi ...
Yang, Xin-She
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

PENGARUH VARIASI KOMPOSISI DAN PEMADATAN SERASAH DAUN DAN SAMPAH PLASTIK TERHADAP PROSES DEKOMPOSISI SERASAH DAUN DENGAN MENGGUNAKAN AKTIVATOR KOMPOS MATANG [PDF]

open access: yes, 2017
ABSTRAK Penelitian ini bertujuan untuk mengetahui pengaruh sampah plastik terhadap proses dekomposisi serasah daun yang terjadi pada landfill TPST Undip dengan penambahan aktivator kompos matang.
Fatimah, Maulia
core  

Macro- and microscale gaseous diffusion in a Stagnic Luvisol as affected by compaction and reduced tillage [PDF]

open access: yes, 2008
Intensification of mechanical agriculture has increased the risk for soil compaction and deformation. Simultaneously, reduced tillage practices have become popular due to energy saving and environmental concerns, as they may strengthen and improve the ...
Fazekas-Becker, Orsolya   +2 more
core   +3 more sources

Influence of Partial and Total Replacement of Used Foundry Sand in Self-Compacting Concrete [PDF]

open access: gold, 2022
G. Garcia   +5 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

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