Results 111 to 120 of about 1,125,486 (341)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Locally compact, $\omega_1$-compact spaces
An $\omega_1$-compact space is a space in which every closed discrete subspace is countable. We give various general conditions under which a locally compact, $\omega_1$-compact space is $\sigma$-countably compact, i.e., the union of countably many countably compact spaces. These conditions involve very elementary properties.
Nyikos, Peter, Zdomskyy, Lyubomyr
openaire +2 more sources
Approximating compact and weakly compact operators [PDF]
REMARKS. To place the theorem in context consider all operators as mapping the Banach space X into the Banach space Y and consider the topology a to be that of almost uniform convergence on the unit ball of X utilizing the norm topology on Y. The second theorem gives a similar result for weakly compact operators.
openaire +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Effects of Tidal Resonances in Coalescing Compact Binary Systems [PDF]
Masaru Shibata
openalex +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
ObjectiveUrban development has always been intricately linked with the natural environment, characterized by a dynamic and complex interplay involving the dependence on, and utilization, management, degradation, and restoration of natural resources. This
Xiangrong WANG, Jinshi ZHANG
doaj +1 more source
H
H. Bravo–Alfaro +4 more
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

