Results 1 to 10 of about 459,901 (268)

Comparative characteristics of the vaginal and endometrial microbiome in patients with secondary infertility associated with a uterine scar niche after cesarean section [PDF]

open access: yesГинекология, 2021
Aim. To compare the vaginal and endometrial microbiome in patients with cesarean scar niche (both in the presence of specific complaints of secondary infertility in combination with a niche with stagnant contents, and in the absence of such ...
Mark A. Kurtser   +5 more
doaj   +1 more source

Comparative evaluation of the energy and economic efficiency of vapor compression heat pumps in modernization of large chemical and oil refining industries. Part 1 [PDF]

open access: yesОмский научный вестник: Серия "Авиационно-ракетное и энергетическое машиностроение", 2023
The question of the feasibility of increasing the energy efficiency of large chemical and oil refining industries by replacing furnace heaters of process heat carriers and raw materials with vapor compression heat pumps is considered.
V. L. Yusha   +2 more
doaj   +1 more source

The prevalence of chronic endometritis in patients with secondary infertility associated with a caesarean scar niche [PDF]

open access: yesГинекология, 2022
Background. The trend towards an increase in the number of caesarean sections (CS) has led to the fact that many women are more likely to plan a second pregnancy with a caesarean scar niche.
Mark A. Kurtser   +4 more
doaj   +1 more source

Comparative evaluation of the energy and economic efficiency of vapor compression heat pumps in modernization of large chemical and oil refining industries. Part 2 [PDF]

open access: yesОмский научный вестник: Серия "Авиационно-ракетное и энергетическое машиностроение", 2023
The question of the expediency of increasing the energy efficiency of a large chemical and oil refining industry by using process heat carriers and raw materials as heaters of vapor compression heat pumps based on systems for recuperating heat process ...
V. L. Yusha   +2 more
doaj   +1 more source

The Hepatitis B Virus Interactome: A Comprehensive Overview

open access: yesFrontiers in Microbiology, 2021
Despite the availability of a prophylactic vaccine, chronic hepatitis B (CHB) caused by the hepatitis B virus (HBV) is a major health problem affecting an estimated 292 million people globally.
Ellen Van Damme   +5 more
doaj   +1 more source

Alternative Functional In Vitro Models of Human Intestinal Epithelia

open access: yesFrontiers in Pharmacology, 2013
Physiologically relevant sources of absorptive intestinal epithelial cells are crucial for human drug transport studies. Human adenocarcinoma-derived intestinal cell lines, such as Caco-2, offer conveniences of easy culture maintenance and scalability ...
Amanda L Kauffman   +5 more
doaj   +1 more source

Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology

open access: yesNature Communications, 2020
Small molecule polyamines participate in diverse aspects of cell growth and differentiation and are known to regulate ion channel gating. Here authors reveal that cellular polyamines control nicotinic acetylcholine receptor (nAChR) biogenesis, and either
Madhurima Dhara   +6 more
doaj   +1 more source

An exposure‐response analysis of ponesimod clinical efficacy in a randomized phase III study in patients with relapsing multiple sclerosis

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2022
The efficacy of ponesimod and teriflunomide for the treatment of relapsing multiple sclerosis (MS) was compared in a randomized phase III trial. This study explores the exposure‐response (E‐R) relationships of efficacy end points (annualized relapse rate
Belén Valenzuela   +6 more
doaj   +1 more source

Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser422 containing epitope on pathological tau

open access: yesActa Neuropathologica Communications, 2018
Aggregation of tau protein and spreading of tau aggregates are pivotal pathological processes in a range of neurological disorders. Accumulating evidence suggests that immunotherapy targeting tau may be a viable therapeutic strategy.
Jeroen van Ameijde   +18 more
doaj   +1 more source

α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins

open access: yesNature Communications, 2019
The α7 nicotinic acetylcholine receptor (nAChR) plays a major role in shaping the activity of neuronal circuits and contributes to the pathophysiology of several neurological disorders.
G. Brent Dawe   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy