Animals, 2020 OA is quite common in companion animals, especially in large breed dogs and horses. Collagen, the most abundant protein of mammals, has specific connective tissue types for skin, bones, reticulate, basal lamina, bones, cell surfaces, while type II ...
Hasan Gencoglu +3 more
doaj +1 more source
Frontiers in Medical Technology, 2022 Animal organoid models derived from farm and companion animals have great potential to contribute to human health as a One Health initiative, which recognize a close inter-relationship among humans, animals and their shared environment and adopt multi ...
Minae Kawasaki +4 more
doaj +1 more source
Quantification of plasmodesmatal endoplasmic reticulum coupling between sieve elements and companion cells using fluorescence redistribution after photobleaching [PDF]
, 2006 Transgenic tobacco (Nicotiana tabacum) was studied to localize the activity of phloem loading during development and to establish whether the endoplasmic reticulum (ER) of the companion cell (CC) and the sieve element (SE) reticulum is continuous by ...
Roberts, Alison G. +6 more
core +1 more source
p57(Kip2) imposes the reserve stem cell state of gastric chief cells
, 2022 Adult stem cells constantly react to local changes to ensure tissue homeostasis. In the main body of the stomach, chief cells produce digestive enzymes; however, upon injury, they undergo rapid proliferation for prompt tissue regeneration.
Ju, Young Seok +24 more
core +1 more source
Long-Term Adult Feline Liver Organoid Cultures for Disease Modeling of Hepatic Steatosis
Stem Cell Reports, 2017 Summary: Hepatic steatosis is a highly prevalent liver disease, yet research is hampered by the lack of tractable cellular and animal models. Steatosis also occurs in cats, where it can cause severe hepatic failure.
Hedwig S. Kruitwagen +20 more
doaj +1 more source
Epithelial–mesenchymal plasticity and circulating tumor cells: Travel companions to metastases [PDF]
Developmental Dynamics, 2017 Epithelial–mesenchymal transitions (EMTs) associated with metastatic progression may contribute to the generation of hybrid phenotypes capable of plasticity. This cellular plasticity would provide tumor cells with an increased potential to adapt to the different microenvironments encountered during metastatic spread.
Francart, Marie‐emilie +6 more
openaire +3 more sources
Mesenchymal cell invasion requires cooperative regulation of persistent microtubule growth by SLAIN2 and CLASP1 [PDF]
, 2016 Microtubules regulate signaling, trafficking, and cell mechanics, but the respective contribution of these functions to cell morphogenesis and migration in 3D matrices is unclear.
Noordstra, Ivar +15 more
core +2 more sources
Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids
Stem Cell Reports, 2015 The recent development of 3D-liver stem cell cultures (hepatic organoids) opens up new avenues for gene and/or stem cell therapy to treat liver disease.
Sathidpak Nantasanti +18 more
doaj +1 more source
Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.
, 2022 Clear cell renal cell carcinoma (ccRCC) is characterized by near-universal loss of the short arm of chromosome 3, deleting several tumor suppressor genes. We analyzed whole genomes from 95 biopsies across 33 patients with clear cell renal cell carcinoma.
Raine, K +47 more
core +1 more source
Cell Migration with Multiple Pseudopodia: Temporal and Spatial Sensing Models [PDF]
, 2013 Cell migration triggered by pseudopodia (or “false feet”) is the most used method of locomotion. A 3D finite element model of a cell migrating over a 2D substrate is proposed, with a particular focus on the mechanical aspects of the biological phenomenon.
ALLENA, Rachele
core +1 more source