Results 21 to 30 of about 56,758 (258)
Biology, 2021 Companion animals with naturally occurring cancers can provide an advantageous model for cancer research and in particular anticancer drug development.
Antonio Giuliano
doaj +1 more source
The companions: regulatory T cells and gene therapy [PDF]
Immunology, 2009 SummaryUndesired immunological responses to products of therapeutic gene replacement have been obstacles to successful gene therapy. Understanding such responses of the host immune system to achieve immunological tolerance to a transferred gene product is therefore crucial.
Saman, Eghtesad +2 more
openaire +2 more sources
Vagrant Stem Cells Draft Their Gene Companions [PDF]
Cell Stem Cell, 2010 In a recent issue of Nature Medicine, Ryan et al. (2010) uncover genetic modifiers of G-CSF responses by hematopoietic progenitors. The authors document a negative role of EGFR signaling and, provided an analogous pathway functions in humans, propose a potential new angle to promote clinical blood stem cell mobilization.
Bonig, Halvard, Papayannopoulou, Thalia
openaire +2 more sources
Frontiers in Veterinary Science, 2021 In the past decade, the potential to translate scientific discoveries in the area of regenerative therapeutics in veterinary species to novel, effective human therapies has gained interest from the scientific and public domains.
Boaz Arzi +10 more
doaj +1 more source
Favipiravir Suppresses Zika Virus (ZIKV) through Activity as a Mutagen
Microorganisms, 2023 In a companion paper, we demonstrated that the nucleoside analogue favipiravir (FAV) suppressed Zika virus (ZIKV) replication in three human-derived cell lines—HeLa, SK-N-MC, and HUH-7.
Evelyn J. Franco +5 more
doaj +1 more source
A pocket companion to cell-free DNA (cfDNA) preanalytics
Tumor Biology, 2023 The cumulative pool of cell-free DNA (cfDNA) molecules within bodily fluids represents a highly dense and multidimensional information repository. This “biological mirror” provides real-time insights into the composition, function, and dynamics of the diverse genomes within the body, enabling significant advancements in personalized molecular medicine.
Abel J, Bronkhorst, Stefan, Holdenrieder
openaire +2 more sources
Cells, 2020 The shortage of liver organ donors is increasing and the need for viable alternatives is urgent. Liver cell (hepatocyte) transplantation may be a less invasive treatment compared with liver transplantation.
Hedwig S. Kruitwagen +22 more
doaj +1 more source
Induction of sucrose synthase in the phloem of phytoplasma infected maize
Biologia Plantarum, 2011 In this study, we have analyzed the expression of the low oxygen inducible sucrose synthase isozyme SH1 (SUS-SH1) in the phloem of maize (Zea mays L.) infected with maize bushy stunt phytoplasma.
J. Brzin +3 more
doaj +1 more source
Journal of Veterinary Internal Medicine, 2020 Background Hepatic lipidosis is increasing in incidence in the Western world, with cats being particularly sensitive. When cats stop eating and start utilizing their fat reserves, free fatty acids (FFAs) increase in blood, causing an accumulation of ...
Maya W. Haaker +9 more
doaj +1 more source
Vascular Gene Expression: A Hypothesis
Frontiers in Plant Science, 2013 The phloem is the conduit through which photoassimilates are distributed from autotrophic to heterotrophic tissues and is involved in the distribution of signaling molecules that coordinate plant growth and responses to the environment.
Angélica Concepción eMartínez-Navarro +3 more
doaj +1 more source