Results 61 to 70 of about 56,758 (258)

Cell Differentiation in the Lower Outer Sheath of the Romney Wool Follicle: A Companion Cell Layer [PDF]

Australian Journal of Biological Sciences, 1971
Morphological evidence is presented showing that, in the Romney wool follicle, the layer of cells in the outer root sheath lying next to Henle's layer differentiates in the bulb as a separate and distinct layer from other outer root sheath cells. The term "companion cell layer" is suggested for this layer. Its possible role in the movement of the inner
openaire   +2 more sources

Stem Cells and Regenerative Medicine in Domestic and Companion Animals: A Multispecies Perspective [PDF]

Reproduction in Domestic Animals, 2014
ContentsSince their original isolation, the majority of the work on embryonic stem cells (ESC) has been carried out in mice. While the mouse is an outstanding model for basic research, it also has considerable limitations for translational work, especially in the area of regenerative medicine.
N N, Gonçalves, C E, Ambrósio, J A, Piedrahita   +2 more
openaire   +2 more sources

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Growth Hormone Receptor Regulation in Cancer and Chronic Diseases

Frontiers in Endocrinology, 2020
The GHR signaling pathway plays important roles in growth, metabolism, cell cycle control, immunity, homeostatic processes, and chemoresistance via both the JAK/STAT and the SRC pathways. Dysregulation of GHR signaling is associated with various diseases
Ger J. Strous, Ger J. Strous, Ana Da Silva Almeida, Joyce Putters, Julia Schantl, Magdalena Sedek, Johan A. Slotman, Tobias Nespital, Gerco C. Hassink, Jan A. Mol   +9 more
doaj   +1 more source

Translating stem cell therapies: The role of companion animals in regenerative medicine [PDF]

Wound Repair and Regeneration, 2013
AbstractVeterinarians and veterinary medicine have been integral to the development of stem cell therapies. The contributions of large animal experimental models to the development and refinement of modern hematopoietic stem cell transplantation were noted nearly five decades ago.
Susan W, Volk, Christine, Theoret
openaire   +2 more sources

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Translocation of nuclei and reorientation of the mitotic apparatus in the ontogeny of stomata in Trudescuntia virginiana L.

Acta Societatis Botanicorum Poloniae, 2014
In vitro studies of the ontogeny of stomata of young leaves of Tradescantia virginiana L. showed that: 1) translocation of nuclei, often along long, winding paths took place in companion cell mother cells before the onset of asymmetric mitosis, 2) the ...
Jadwiga A. Tarkowska, Mirosława Ważyńska, Alina A. Jabłonowska   +2 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

Hippo signaling pathway in companion animal diseases, an under investigated signaling cascade

Veterinary Quarterly, 2021
The Hippo pathway is a highly conserved kinase cascade in mammals with the proteins YAP and TAZ as its most important downstream effectors that shuttle between cytoplasma and nucleus.
Shaydee J. Budel, Marloes M. Penning, Louis C. Penning   +2 more
doaj   +1 more source

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark, Kayla L. Foster, Omar Shakeel, Mary C. Shapiro, Shawki L. Qasim, ZoAnn Dreyer, Eric S. Schafer, Ashley M. Butler, Austin L. Brown, Maria Monica Gramatges   +9 more
wiley   +1 more source