Results 111 to 120 of about 5,639,819 (287)

Comparative analysis of the seismic hazard of Central China [PDF]

open access: yes, 2008
Seismic hazard assessment is globally recognised as a tool in identifying levels of earthquake ground shaking within an area. However, methodologies for seismic hazard calculation are wide ranging and produce variations in results and maps.
Burton, Paul W., Cole, Stephen W.
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Green manuring for tropical organic cropping – A comparative analysis [PDF]

open access: yes, 2008
Green manuring is an essential component of tropical organic farming. Field studies evaluated the use of three legumes as in situ or ex situ green manures, along with a nonlegume green manure and a control to ascertain their impacts on soil properties ...
Freyer, Prof.Dr. Bernhard   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Informatics Security Metrics Comparative Analysis [PDF]

open access: yes
The informatics security concept is defined. For informatics applications which have a classical structure, the development, current use, maintenance, and reengineering particularities are described for distributed systems and m-applications. Metrics are
Ion IVAN, Luckacs BREDA
core  

A comparative reliability analysis of ETCS train radio communications [PDF]

open access: yes, 2005
StoCharts have been proposed as a UML statechart extension for performance and dependability evaluation, and were applied in the context of train radio reliability assessment to show the principal tractability of realistic cases with this approach.
Hermanns, H., Jansen, D.N., Usenko, Y.S.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Shifts in plant functional trait dynamics in relation to soil microbiome in modern and wild barley

open access: yesPlants, People, Planet
Societal Impact Statement Understanding domestication's impact on crop root traits and interactions with soil microbiomes is vital for improving crop resilience and agricultural sustainability.
Amit Kumar   +9 more
doaj   +1 more source

Assessing developmental toxicity and non-CYP mediated biotransformation of two anti-epileptics and their human metabolites in zebrafish embryos and larvae

open access: yesCurrent Research in Toxicology
Zebrafish embryo-based assays are a promising alternative for animal testing to screen new compounds for developmental toxicity. However, recent studies in zebrafish embryos showed an immature intrinsic cytochrome P450 (CYP)-mediated biotransformation ...
Jente Hoyberghs   +5 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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