Results 141 to 150 of about 1,657,556 (272)

Comparability of European League Against Rheumatology-Recommended Pharmacological Treatments of Oral Ulcers Associated with Behçet’s Disease: A Systematic Literature Review of Randomized Controlled Trials

Open Access Rheumatology: Research and Reviews, 2020
Tara Nazareth,1 Erin M Hart,2 Sarah M Ronnebaum,3 Sandhya Mehta,4 Dipen A Patel,3 Ina Kötter5 1Amgen Inc., Thousand Oaks, CA, USA; 2Pharmerit - an OPEN Health Company, New York, NY, USA; 3Pharmerit - an OPEN Health Company, Bethesda, MD, USA ...
Nazareth T, Hart EM, Ronnebaum SM, Mehta S, Patel DA, Kötter I   +5 more
doaj  

Heterogeneity of outcomes in randomized controlled trials on implant prosthodontic therapy is hindering comparative effectiveness research: meta-research study. [PDF]

BMC Oral Health, 2023
Vardić A, Puljak L, Galić T, Viskić J, Kuliš E, Poklepović Peričić T.   +5 more
europepmc   +1 more source

Accreditation of health services: is it money and time well spent? [PDF]

The research evidence shows that accreditation is a useful tool for stimulating improvements in the quality and safety of health services. Accreditation programs are deployed widely to monitor and promote safety and quality in healthcare.
Anne-Marie Boxall, David Greenfield, Jeffrey Braithwaite, Krister Partel, Reece Hinchcliff   +4 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Feasibility of Conducting Comparative Effectiveness Research and Validation of a Clinical Disease Activity Score for Chronic Nonbacterial Osteomyelitis. [PDF]

J Rheumatol, 2023
Wu EY, Oliver M, Scheck J, Lapidus S, Akca UK, Yasin S, Stern SM, Insalaco A, Pardeo M, Simonini G, Marrani E, Wang X, Huang B, Kovalick LK, Rosenwasser N, Casselman G, Liau A, Shao Y, Yang C, Mosa DM, Tucker L, Girschick H, Laxer RM, Akikusa JD, Hedrich CM, Onel K, Dedeoglu F, Twilt M, Ferguson PJ, Ozen S, Zhao Y.   +30 more
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Missing data matter: an empirical evaluation of the impacts of missing EHR data in comparative effectiveness research. [PDF]

J Am Med Inform Assoc, 2023
Zhou Y, Shi J, Stein R, Liu X, Baldassano RN, Forrest CB, Chen Y, Huang J.   +7 more
europepmc   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Utility of serum cytokine testing to differentiate complicated common variable immunodeficiency in resource limited settings

Journal of Allergy and Clinical Immunology: Global
Background: Common variable immunodeficiency (CVID) is the most common, symptomatic inborn error of immunity (IEI) worldwide. CVID diagnosis requires lymphocyte subset analysis by flow cytometry to delineate risk for autoimmune and inflammatory (AI ...
Aditi Jogdand, BS, Karen M. Gilbert, PhD, Joseph S. Hong, BS, Andrew J. Pak, BS, Katherine Liu, BA, Uhuru Kamau, MS, Neha V. Khairnar, MS, MBA, Henry C. Ssemaganda, MD, MS, Daniel DiGiacomo, MD, MPH, Sara Barmettler, MD, MPH, Mei-Sing Ong, PhD, Jocelyn R. Farmer, MD, PhD   +11 more
doaj   +1 more source

Identifying surrogate markers in real-world comparative effectiveness research. [PDF]

Stat Med, 2022
Han L, Wang X, Cai T.
europepmc   +1 more source