Results 131 to 140 of about 2,755,876 (359)
Genus-Wide Comparative Genomics of Malassezia Delineates Its Phylogeny, Physiology, and Niche Adaptation on Human Skin
PLoS Genetics, 2015 Malassezia is a unique lipophilic genus in class Malasseziomycetes in Ustilaginomycotina, (Basidiomycota, fungi) that otherwise consists almost exclusively of plant pathogens.Guangxi Wu, He Zhao, Chenhao Li, Menaka Priyadarsani Rajapakse, Wing-Cheong Wong, Jun Xu, C. Saunders, N. Reeder, R. Reilman, A. Scheynius, Sheng Sun, B. Billmyre, Wenjun Li, A. Averette, P. Mieczkowski, J. Heitman, B. Theelen, Markus S. Schröder, P. F. de Sessions, G. Butler, S. Maurer-Stroh, T. Boekhout, N. Nagarajan, T. Dawson +23 moresemanticscholar +1 more sourceMolecular Genetic Aspects of Oligodendrogliomas Including Analysis by Comparative Genomic Hybridization [PDF]
, 1999 Sandra H. Bigner, Mark R. Matthews, Binish Rasheed, Rodney N. Wiltshire, Henry S. Friedman, Allan H. Friedman, Timothy T. Stenzel, Donald M. Dawes, Roger E. McLendon, Darell D. Bigner +9 moreopenalex +1 more sourceComparative genomics and prediction of conditionally dispensable sequences in legume–infecting Fusarium oxysporum formae speciales facilitates identification of candidate effectors
BMC Genomics, 2016 Soil-borne fungi of the Fusarium oxysporum species complex cause devastating wilt disease on many crops including legumes that supply human dietary protein needs across many parts of the globe.Angela H Williams, Angela H Williams, Mamta Sharma, L. Thatcher, Sarwar Azam, James K. Hane, James K. Hane, Jana Sperschneider, Brendan N Kidd, Jonathan P. Anderson, Jonathan P. Anderson, R. Ghosh, Gagan Garg, J. Lichtenzveig, H. Kistler, Terrance Shea, Sarah K. Young, Sally-Anne Buck, L. Kamphuis, L. Kamphuis, R. Saxena, S. Pande, Li‐Jun Ma, R. Varshney, R. Varshney, Karam B. Singh, Karam B. Singh +26 moresemanticscholar +1 more sourceThe atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger +17 morewiley +1 more sourceComparative genomics reveals insights into avian genome evolution and adaptation
Science, 2014 Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species representing all major extant clades.Guojie Zhang, Cai Li, Qiye Li, Bo Li, D. Larkin, Chul Lee, Jay F. Storz, Agostinho Antunes, Matthew J. Greenwold, Robert W. Meredith, A. Ödeen, Jianwei Cui, Q. Zhou, Luohao Xu, Hailin Pan, Zongji Wang, Li-jun Jin, Pei Zhang, Haofu Hu, Wei-wei Yang, Jiang Hu, Jin Xiao, Zhikai Yang, Yang Liu, Qiaolin Xie, Hao Yu, J. Lian, Ping Wen, Fang Zhang, Hui Li, Yongli Zeng, Zijun Xiong, Shiping Liu, Long Zhou, Zhiyong Huang, Na An, Jie Wang, Q. Zheng, Yingqi Xiong, Guangbiao Wang, Bosheng Wang, Jingjing Wang, Yu Fan, R. D. da Fonseca, Alonzo Alfaro-Núñez, Mikkel Schubert, L. Orlando, T. Mourier, Jason T. Howard, Ganeshkumar Ganapathy, Andreas R. Pfenning, O. Whitney, M. Rivas, Erina Hara, Julia Smith, M. Farré, Jitendra Narayan, G. Slavov, Michael N Romanov, Rui Borges, J. Machado, Imran Khan, M. Springer, J. Gatesy, F. Hoffmann, J. Opazo, O. Håstad, R. Sawyer, Heebal Kim, Kyu-Won Kim, H. Kim, Seoae Cho, Ning Li, Yinhua Huang, M. Bruford, Xiangjiang Zhan, Andrew Dixon, Mads F Bertelsen, E. Derryberry, Wesley C. Warren, Richard K. Wilson, Shengbin Li, David A. Ray, R. Green, Stephen J. O’Brien, Darren K. Griffin, Warren E. Johnson, David Haussler, Oliver A. Ryder, E. Willerslev, G. Graves, P. Alström, J. Fjeldså, D. Mindell, Scott V. Edwards, E. Braun, C. Rahbek, David W Burt, P. Houde, Yong Zhang, Han Yang, J. Wang, Erich D. Jarvis, M. T. P. Gilbert, J. Wang, Emanuel Maldonado +105 moresemanticscholar +1 more sourceA large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas +20 morewiley +1 more sourceComparative genomics identifies the Magnaporthe oryzae avirulence effector AvrPi9 that triggers Pi9-mediated blast resistance in rice.
New Phytologist, 2015 We identified the Magnaporthe oryzae avirulence effector AvrPi9 cognate to rice blast resistance gene Pi9 by comparative genomics of requisite strains derived from a sequential planting method.Jun Wu, Yanjun Kou, Jiandong Bao, Ya Li, Mingzhi Tang, Xiaoli Zhu, A. Ponaya, G. Xiao, Jinbin Li, Chenyun Li, Min-Young Song, C. Cumagun, Q. Deng, G. Lu, J. Jeon, Naweed I. Naqvi, Bo Zhou +16 moresemanticscholar +1 more source