Results 111 to 120 of about 3,218,020 (355)

Ammonia‐oxidising archaea living at low pH: Insights from comparative genomics

Environmental Microbiology, 2017
Summary Obligate acidophilic members of the thaumarchaeotal genus Candidatus Nitrosotalea play an important role in nitrification in acidic soils, but their evolutionary and physiological adaptations to acidic environments are still poorly understood ...
C. Herbold, L. Lehtovirta-Morley, Man-Young Jung, N. Jehmlich, B. Hausmann, P. Han, A. Loy, M. Pester, L. Sayavedra-Soto, S. Rhee, J. Prosser, G. Nicol, M. Wagner, C. Gubry-Rangin   +13 more
semanticscholar   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Mapping quantitative trait loci and identification of genes that control fatness in poultry

, 2002
Chicken genomics has benefited from the rapid technological advances in the genomics of model organisms and man. A number of resources and approaches are now well established, in the chicken, including genetic markers and maps (both genetic and physical),
Hocking, Paul M, Hocking, PM, Burt, DW, Burt, David W   +3 more
core   +1 more source

TAKosch/Amphibian-Comparative-Genomics: Scripts for Comparative analysis of amphibian genomes paper

, 2023
These are the house-made bash scripts used to conduct the analyses in the paper: Kosch, T.A., Crawford, A.J., Muller, R.L., Wollenberg Valero, K.C., Rodriguez, A., O'Connell, L.A., Young, N.D., and Skeratt, L.F. Comparative analysis of amphibian genomes:
Tiffany Kosch
core   +1 more source

OrthoInspector 3.0: open portal for comparative genomics

Nucleic Acids Res., 2018
OrthoInspector is one of the leading software suites for orthology relations inference. In this paper, we describe a major redesign of the OrthoInspector online resource along with a significant increase in the number of species: 4753 organisms are now ...
Yannis Nevers, Arnaud Kress, Audrey Defosset, R. Ripp, Benjamin Linard, J. Thompson, O. Poch, O. Lecompte   +7 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Exploring the Zoonotic Potential of Mycobacterium avium Subspecies paratuberculosis through Comparative Genomics. [PDF]

, 2011
A comparative genomics approach was utilised to compare the genomes of Mycobacterium avium subspecies paratuberculosis (MAP) isolated from early onset paediatric Crohn's disease (CD) patients as well as Johne's diseased animals.
Michalski Wojtek P., Bull, TJ, Seemann, Torsten, Seemann Torsten, Bull, Tim, Tim J Bull, Michalski, WP, Seemann, T, Dieter M Bulach, Torsten Seemann, Wynne, JW, Josef Wagner, Kirkwood, Carl, Michalski, Wojtek, James W Wynne, Wynne James W., Wagner Josef, James W. Wynne, Carl D Kirkwood, Wojtek P Michalski, Bulach Dieter M., Bulach, Dieter, Kirkwood, CD, Wynne, James, Dieter M. Bulach, Bulach, DM, Bull Tim J., Tim J. Bull, Carl D. Kirkwood, Kirkwood Carl D., Wagner, J, Wojtek P. Michalski, Wagner, Josef   +32 more
core   +1 more source

Genomic analysis finds no evidence of canonical eukaryotic DNA processing complexes in a free-living protist

Nature Communications, 2021
The mechanisms for replicating and segregating DNA are highly conserved across eukaryotes. A comparative genomic analysis of a free-living protist finds a surprising lack of protein complexes involved in these processes, suggesting that the organism uses
Dayana E. Salas-Leiva, Eelco C. Tromer, Bruce A. Curtis, Jon Jerlström-Hultqvist, Martin Kolisko, Zhenzhen Yi, Joan S. Salas-Leiva, Lucie Gallot-Lavallée, Shelby K. Williams, Geert J. P. L. Kops, John M. Archibald, Alastair G. B. Simpson, Andrew J. Roger   +12 more
doaj   +1 more source

Comparative genomics of Leishmania (Mundinia)

BMC Genomics, 2019
Trypanosomatids of the genus Leishmania are parasites of mammals or reptiles transmitted by bloodsucking dipterans. Many species of these flagellates cause important human diseases with clinical symptoms ranging from skin sores to life-threatening damage
A. Butenko, A. Kostygov, J. Sádlová, Yuliya Kleschenko, Tomáš Bečvář, Lucie Podešvová, Diego H. Macedo, David Žihala, J. Lukeš, P. Bates, P. Volf, F. Opperdoes, V. Yurchenko   +12 more
semanticscholar   +1 more source

PhycoCosm, a comparative algal genomics resource

Nucleic Acids Res., 2020
Algae are a diverse, polyphyletic group of photosynthetic eukaryotes spanning nearly all eukaryotic lineages of life and collectively responsible for ∼50% of photosynthesis on Earth.
I. Grigoriev, Richard D. Hayes, Sara Calhoun, Bishoy Kamel, Alice Wang, Steven R. Ahrendt, Serge Dusheyko, Roman Nikitin, S. Searle, A. Salamov, Igor Shabalov, A. Kuo   +11 more
semanticscholar   +1 more source