Results 251 to 260 of about 423,333 (300)

Comparative genomics reveals the high diversity and adaptation strategies of Polaromonas from polar environments. [PDF]

BMC Genomics
Du Y, He C, Lloyd KG, Vishnivetskaya TA, Cui H, Li B, Gong D, Fan X, Zhang D, Jiang H, Liang R.   +10 more
europepmc   +1 more source

Comparative Genomic Hybridization Analysis of Cisplatin-Resistant Ovarian Carcinoma Cells.

, 2000
Ritsuko Arai, Mohammad Ghazizadeh, Oichi Kawanami   +2 more
openalex   +2 more sources

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Chromosome-length genome assembly of the critically endangered Mountain bongo (Tragelaphus eurycerus isaaci): a resource for conservation and comparative genomics. [PDF]

G3 (Bethesda)
Holm KM, Koepfli KP, Pukazhenthi BS, Ratan A, Fryxell KJ, Pham M, Weisz D, Dudchenko O, Aiden EL, Lim HC.   +9 more
europepmc   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Comparative Genomics Insights Into the Evolutionary Disparities Between Nitroplast-Evolved Ecotype UCYN-A2 and Its Closest Relative UCYN-A1. [PDF]

Ecol Evol
Han S, Zhang S, Ge W, Yang J, Peng H, Gao J, Zhang M, Xiao Y, Du D, Kan X.   +9 more
europepmc   +1 more source

3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes

Advanced Biology, EarlyView.
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins, Ah Joung Yu, Cheryl T. Gomillion   +2 more
wiley   +1 more source

Author Correction: Comparative genomics reveal a novel phylotaxonomic order in the genus Fusobacterium. [PDF]

Commun Biol
Molteni C, Forni D, Cagliani R, Sironi M.   +3 more
europepmc   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source