Results 301 to 310 of about 449,093 (327)
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2017
Over the last quarter of a century it has become clear that RNA is much more than just a boring intermediate in protein expression. Ancient RNAs still appear in the core information metabolism and comprise a surprisingly large component in bacterial gene regulation.
Backofen, Rolf +3 more
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Over the last quarter of a century it has become clear that RNA is much more than just a boring intermediate in protein expression. Ancient RNAs still appear in the core information metabolism and comprise a surprisingly large component in bacterial gene regulation.
Backofen, Rolf +3 more
openaire +6 more sources
Comparative Genomic Hybridization
Current Protocols in Cell Biology, 2004AbstractComparative genomic hybridization (CGH) is a screening method based on fluorescence in situ hybridization (FISH). In contrast to conventional FISH, the metaphase target is derived from a normal peripheral blood lymphocyte culture. This target is hybridized to the test or tumor DNA, which is labeled/detected by one fluorochrome (i.e., green ...
Jane, Bayani, Jeremy A, Squire
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2017
Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. Increasingly, such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, König +2 more
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Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. Increasingly, such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, König +2 more
openaire +2 more sources
Comparative mycobacterial genomics
Current Opinion in Microbiology, 1998Genomics is providing us with a mass of information about the biochemistry, physiology and pathogenesis of Mycobacterium tuberculosis and Mycobacterium leprae. Comparison of the two genome sequences is mutually enriching and indicates that the M. leprae genome appears to have undergone shrinkage and large-scale gene inactivation, which may account for ...
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Genome Mapping in Plant Comparative Genomics
Trends in Plant Science, 2016Genome mapping produces fingerprints of DNA sequences to construct a physical map of the whole genome. It provides contiguous, long-range information that complements and, in some cases, replaces sequencing data. Recent advances in genome-mapping technology will better allow researchers to detect large (>1kbp) structural variations between plant ...
Lindsay, Chaney +3 more
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Genome screening by comparative genomic hybridization
Trends in Genetics, 1997Comparative genomic hybridization (CGH) provides a molecular cytogenetic approach for genome-wide scanning of differences in DNA sequence copy number. The technique is now attracting wide-spread interest, especially among cancer researchers. The rapidly expanding database of CGH publications already covers about 1500 tumors and is beginning to reveal ...
F, Forozan +4 more
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Comparative genomics: the bacterial pan-genome
Current Opinion in Microbiology, 2008Bacterial genome sequencing has become so easy and accessible that the genomes of multiple strains of more and more individual species have been and will be generated. These data sets provide for in depth analysis of intra-species diversity from various aspects.
Tettelin H, Riley D, Cattuto C, Medini D
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Comparative Genomic Hybridization
2003Numerical genetic changes can be most easily examined by simply preparing metaphase chromosomes and counting the number of chromosomes in the spread. Unfortunately, it is often impossible to obtain high-quality metaphase preparations from samples, especially solid tumors.
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Comparative Genomic Hybridization
2001Comparative genomic hybridization (CGH) allows a genome-wide survey of the relative copy number of tumor DNA in a single hybridization. The tumor-cell DNA (Test DNA) is hybridized together with a sex-matched normal DNA (Reference DNA) onto normal metaphase spreads.
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Newly sequenced genomes are being added to the tree of life at an unprecedented fast pace. A large proportion of such new genomes are phylogenetically close to previously sequenced and annotated genomes. In other cases, whole clades of closely related species or strains ought to be annotated simultaneously.
Stefanie, Nachtweide +2 more
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Stefanie, Nachtweide +2 more
openaire +2 more sources