Results 81 to 90 of about 3,218,020 (355)

Comparative genomics defines the core genome of the growing N4-like phage genus and identifies N4-like Roseophage specific genes [PDF]

open access: yes, 2014
Two bacteriophages, RPP1 and RLP1, infecting members of the marine Roseobacter clade were isolated from seawater. Their linear genomes are 74.7 and 74.6 kb and encode 91 and 92 coding DNA sequences, respectively.
Schäfer, Hendrik   +11 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Gene family assignment-free comparative genomics

open access: yes, 2012
Dörr D, Thévenin A, Stoye J. Gene family assignment-free comparative genomics. BMC Bioinformatics. 2012;13(Suppl 19: Proc.
Jens Stoye   +7 more
core   +1 more source

Systematic Screening of Commonly Used Commercial Transfection Reagents towards Efficient Transfection of Single-Stranded Oligonucleotides

open access: yesMolecules, 2018
Non-viral vector-mediated transfection is a core technique for in vitro screening of oligonucleotides. Despite the growing interests in the development of oliogonucleotide-based drug molecules in recent years, a comprehensive comparison of the ...
Tao Wang   +3 more
doaj   +1 more source

Genetic Variation, Comparative Genomics, and the Diagnosis of Disease

open access: yesNew England Journal of Medicine, 2019
Uncharted Regions of the Human Genome The genome is not akin to a string of fixed length. Many large segments of DNA may be present or absent — a major contributor to pathogenic genomic variation.
E. Eichler
semanticscholar   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The genetics of symbiotic nitrogen fixation: Comparative genomics of 14 rhizobia strains by resolution of protein clusters

open access: yes, 2012
The symbiotic relationship between legumes and nitrogen fixing bacteria is critical for agriculture, as it may have profound impacts on lowering costs for farmers, on land sustainability, on soil quality, and on mitigation of greenhouse gas emissions ...
John Howieson   +14 more
core   +1 more source

Whole genome comparative studies between chicken and turkey and their implications for avian genome evolution [PDF]

open access: yes, 2008
BACKGROUND: Comparative genomics is a powerful means of establishing inter-specific relationships between gene function/location and allows insight into genomic rearrangements, conservation and evolutionary phylogeny.
Griffin, D.K.   +73 more
core   +1 more source

Comparative genomics of the mycobacteria

open access: yesInternational Journal of Medical Microbiology, 2000
The genus mycobacteria includes two important human pathogens Mycobacterium tuberculosis and Mycobacterium lepra. The former is reputed to have the highest annual global mortality of all pathogens. Their slow growth, virulence for humans and particular physiology makes these organisms extremely difficult to work with.
R, Brosch   +5 more
openaire   +2 more sources

Ebolaviruscomparative genomics [PDF]

open access: yesFEMS Microbiology Reviews, 2015
(Uploaded by Plazi for the Bat Literature Project) The 2014 Ebola outbreak in West Africa is the largest documented for this virus. To examine the dynamics of this genome, we compare more than 100 currently available ebolavirus genomes to each other and to other viral genomes.
Jun, Se Ran   +14 more
openaire   +3 more sources

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