Results 141 to 150 of about 663,472 (214)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Tai chi in mental health interventions: a narrative review comparing its role with pharmacotherapy and psychotherapy. [PDF]

Front Psychol
Zhang X, Wei J, Xiu T.
europepmc   +1 more source

Seriality and Texts for Young People: The Compulsion to RepeatBook review of Mavis Reimer, Nyala Ali, Deanna England and Melanie Dennis Unrau, eds. Seriality and Texts for Young People: The Compulsion to Repeat. Critical Approaches to Children's Literature. Palgrave MacMillan, London, England, 2014

Barnelitterært Forskningstidsskrift, 2015
Maria Nilson
doaj   +1 more source

International Publication Trends of Studies Comparing Total Ankle Arthroplasty and Ankle Arthrodesis: A Systematic Literature Review. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Randsborg PH, Lawson T, Jiang H.
europepmc   +1 more source

Letter to the Editor: Indication-Specific Cost-Effectiveness of Empagliflozin Versus Dapagliflozin: Implications for Clinical and Policy Decision-Making. [PDF]

Hosp Pharm
Belančić A.
europepmc   +1 more source

RUTA: a new kind of compass rose

Tapuya
Julia Sushytska
doaj   +1 more source

Endoscopic Spine Surgery: A Scoping Review of the Literature. [PDF]

Global Spine J
Mulhall D, Kow CY, Veilleux C, Oliveira Masson A, Casha S, du Plessis S, Thomas K, Yang MMH.   +7 more
europepmc   +1 more source

Reforming nursing reimbursement: direct payment models under Iran's Nursing Service Act in a global context. [PDF]

Cost Eff Resour Alloc
Hatefimoadab N, Jaghargh MT, Abbaszadeh A, Sharafi S, Kianian T, Rezaiye M, Ebadi A.   +6 more
europepmc   +1 more source