Results 51 to 60 of about 2,769,215 (334)

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Existence and Multiplicity of Solutions for a Class of Particular Boundary Value Poisson Equations

open access: yesMathematics, 2022
In this paper, a special class of boundary value problems, −▵u=λuq+ur,inΩ,u>0, inΩ,n·∇u+g(u)u=0,on∂Ω, where ...
Songyue Yu, Baoqiang Yan
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Generalized spreading speeds for lattice differential equations with time and space dependence

open access: yesElectronic Journal of Differential Equations, 2019
This article concerns the spatial spreading speeds for lattice differential equations with general time and space dependence. Firstly, we give the concept of spreading speed intervals.
Ning Wang, Zhi-Cheng Wang
doaj  

On Zero-Sum Stochastic Differential Games [PDF]

open access: yes, 2012
We generalize the results of Fleming and Souganidis (1989) on zero sum stochastic differential games to the case when the controls are unbounded. We do this by proving a dynamic programming principle using a covering argument instead of relying on a ...
Bayraktar, Erhan, Yao, Song
core  

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Hopf's lemma for a class of singular/degenerate PDE-s

open access: yes, 2014
This paper concerns Hopf's boundary point lemma, in certain $C^{1,Dini}$-type domains, for a class of singular/degenerate PDE-s, including $p$-Laplacian.
Mikayelyan, Hayk, Shahgholian, Henrik
core   +1 more source

A comparison principle for a Sobolev gradient semi-flow [PDF]

open access: yesCommunications on Pure and Applied Analysis, 2010
23 pages, revised version for ...
T. Blass, R. De La Llave, E. Valdinoci
openaire   +3 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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