Results 51 to 60 of about 2,703,249 (309)
A singular ODE related to quasilinear elliptic equations
Electronic Journal of Differential Equations, 2000 We consider a quasilinear elliptic problem with the natural growth in the gradient. Existence, non-existence, uniqueness, and qualitative properties of positive solutions are obtained. We consider both weak and strong solutions.
Luka Korkut +2 more
doaj
Traffic Network Optimum Principle - Minimum Probability of Congestion Occurrence
, 2010 We introduce an optimum principle for a vehicular traffic network with road bottlenecks. This network breakdown minimization (BM) principle states that the network optimum is reached, when link flow rates are assigned in the network in such a way that ...
Boris S Kerner +9 more
core +1 more source
On the comparison principle in the calculus of variations
Arkiv för Matematik, 1983 On etudie des integrales variationnelles de la forme I(u,D)=∫ D F(x,⊇u(x))dx,DCG.
openaire +3 more sources
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Журнал Белорусского государственного университета: Математика, информатика, 2018 We consider a nonlinear nonlocal parabolic equation ut = Δu + a(x,t)ur∫Ωup(y,t)dy - b(x,t)uq for (x,t) ∈ Ω × (0,+∞) with nonlinear nonlocal boundary condition u(x,t)|∂Ω × (0,+∞) = ∫Ωk(x,y,t)ul(y,t)dy and initial data u(x,0) = u0(x), x ∈ Ω, where r, p, q,
Alexander L. Gladkov +1 more
doaj
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
An eigenvalue problem for the infinity-Laplacian
Electronic Journal of Differential Equations, 2013 In this work, we study an eigenvalue problem for the infinity-Laplacian on bounded domains. We prove the existence of the principal eigenvalue and a corresponding positive eigenfunction.
Tilak Bhattacharya, Leonardo Marazzi
doaj
Capillary surface discontinuities above reentrant corners [PDF]
, 1982 A particular configuration of a vertical capillary tube for which S is the equilibrium interface between two fluids in the presence of a downward pointing gravitational field was investigated.
Korevaar, H. J.
core +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source