Results 101 to 110 of about 690,408 (301)
JAI (Jurnal Anestesiologi Indonesia)Background: Femur fractures are most common in geriatric patients, necessitating careful consideration of perioperative medications. Effective pain management is crucial to minimize neurohormonal stress responses.
Sigit Prasetya Utama +2 more
doaj +1 more source
KIR And HLA Haplotype Analysis in a Family Lacking The KIR 2DL1-2DP1 Genes
Balkan Journal of Medical Genetics, 2015 The killer cell immunoglobulin-like receptor (KIR) gene cluster exhibits extensive allelic and haplotypic diversity that is observed as presence/absence of genes, resulting in expansion and contraction of KIR haplotypes and by allelic variation of ...
Vojvodić Svetlana +1 more
doaj +1 more source
, 2012 Schematic of the lung-specific four-compartment model of 18F-FDG kinetics including an extra-vascular extra-cellular compartment to account for 18F-FDG that is not directly available for phosphorylation, such as 18F-FDG in lung water. Note the functional
Marcos F. Vidal Melo (122835) +6 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Compartment syndrome: challenges and solutions
, 2015 Kohila Sigamoney, Pratima Khincha, Ravi Badge, Nikhil ShahDepartment of Orthopaedics, Wrightington, Wigan and Leigh NHS Foundation Trust, Wigan, UK Abstract: Compartment syndrome is defined as increased pressure within a fibro-osseous space resulting in
Shah N, Sigamoney K, Khincha P, Badge R
core
Calf Compartment Syndrome associated with the Use of an Intra-osseous Line in an Adult Patient: A Case Report [PDF]
, 2016 We present a case of a lower limb compartment syndrome associated with the use of an intra-osseous line inserted into the proximal tibia in an adult patient.
Chua WL, Malhotra R, O’Neill G
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Abdominal Compartment Syndrome
, 2011 The Abdominal Compartment Syndrome (ACS) follows the same pathophysiological principles as other compartment syndromes: increased pressure in a confined space compromises lymphatic and vascular flow leading to ...
Yeh, Daniel D +3 more
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source