Results 241 to 250 of about 1,272,494 (305)

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

Nurses' Perspectives on the Non-Pharmacological Management of Oral Mucositis in Onco-Hematological Care: A Qualitative Content Analysis. [PDF]

Nurs Rep
Diamanti O, Artioli G, Pellegrino P, Bonadies F, Bernardi M, Camuccio A, Pasalic M, Rotondo DA, Dellafiore F.   +8 more
europepmc   +1 more source

GNL3 Orchestrates AR Transcriptional Programs to Drive Castration‐Resistant Prostate Cancer and Immune Evasion

Advanced Science, EarlyView.
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang, Tin Long Cheong, Nitin Narwade, Dandan Dong, Mokan Deng, Zhengqiang Miao, Zhaoqiang Ding, Wenchao Li, Kate Man Kei Lei, Gong‐Hong Wei, Terence Chuen Wai Poon, Chu‐Xia Deng, Edwin Cheung   +12 more
wiley   +1 more source

Competency and Role Development in Advanced Nursing Practice Following a Swiss Master's Cohort Through Education and Early Clinical Practice: Protocol for a Longitudinal Convergent Mixed Methods Study.

JMIR Res Protoc
Braun A, Fringer A, Gattinger H, Eissler C, Zumstein-Shaha M, Beer T, Roes M.   +6 more
europepmc   +1 more source

Friendship: a phenomenological exploration of the lived experience of youth and of peer support workers in Youth FACT (flexible assertive community treatment) services. [PDF]

Int J Qual Stud Health Well-being
Arvesen H, Mjøsund NH, Krane V, Sommer M.   +3 more
europepmc   +1 more source

ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment

Advanced Science, EarlyView.
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu, Meijia Zhang, Maoping Cai, Miao Wang, Ziao Huang, Zesheng Lin, Yixin Liu, Wang Qian, Guopeng Chen, Yuxing Liang, Dongyi Wei, Jing xie, Picheng Yan, Yuanyuan Qu, Yongchang Wei   +14 more
wiley   +1 more source

Mapping competencies of family physicians in primary healthcare: a scoping review. [PDF]

Fam Med Community Health
Saza Salas LD, Hernandez Rincon JA, Hernandez Rincon EH, Ulloa Rodriguez MF, Diaz Quijano DM, Jaimes Peñuela CL.   +5 more
europepmc   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Tailored job coaching for people with severe mental illness living in supported housing settings: A realist approach. [PDF]

PLoS One
Binkhorst J, Dikkers J, Blonk R, van Veldhoven M.   +3 more
europepmc   +1 more source

Development and Validation of Narrative Competence Scale for Medical Students. [PDF]

Perspect Med Educ
Chu SY, Wang HC, Kuo BY, Lin MJ, Chang YC, Lin CW.   +5 more
europepmc   +1 more source