Results 81 to 90 of about 1,272,494 (305)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Competence approach to social rehabilitation of deviant adolescents in special institutions

Психология и право, 2013
We describe the informative aspect of social rehabilitation deviant of adolescents in special institutions, the necessity of considering the competence approach as a conceptual, methodological basis of the special institution activities.
Melnikova M.L.
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Innovation and development prospects of pre-university education of Saratov State Medical University [PDF]

Саратовский научно-медицинский журнал, 2011
The article considers innovative methods used in the pre-university education at Saratov State Medical University and directed to the modernization of educational program.
Popkov V.M., Protopopov A. A., Fedorova L.M., Naumova E.V.   +3 more
doaj  

THE DEVELOPMENT OF STUDENT’S CULTURAL COMPETENCE IN A POST-INDUSTRIAL SOCIETY: THE IMPERATIVES OF CAPITAL APPROACH

Интеграция образования, 2017
Introduction: problems of cultural competence development among higher school students are becoming increasingly important against a decline in a cultural level of an individual in a post-industrial society.
Lyudmila V. Astakhova
doaj   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

A humanistic approach to organizations and to organizational decision-making [PDF]

This paper attempts to take steps towards the formulation of a more human approach to the theory of the firm than the conventional economics-based models.
Rosanas, Josep M.
core  

Formation of professional competence of professionals based integrative approach [PDF]

, 2012
Висвітлено особливості інтегративного мислення фахівця, оцінювання якості професійно-практичної підготовки, дидактика інтегративних курсів у професійній освіті, формування системи професійно-практичних компетенцій, вимоги до формування професійної ...
Дубницька, О.М., Козловська, І.М., Собко, Я.М., Стечкевич, О.О., Якимович, Т. Д.   +4 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Thorstein B. Veblen Precursor of the Competence-Based Approach to the Firm [PDF]

This paper makes the point that Thorstein Veblen should be considered one of the important precursors of the emerging competence-based approach to the firm.
Nicolai J. Foss
core