Results 61 to 70 of about 1,272,494 (305)
Ontological approach for competency-based curriculum analysis
HeliyonThis article is dedicated to the development of a model for competencies within an educational program and its implementation through the use of semantic technologies. The model proposed by the authors is distinctive in that competencies are organized into a hierarchical data structure with arbitrary levels of nesting. Furthermore, the article presents
Marek Milosz +5 more
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
RUDN Journal of Ecology and Life Safety, 2012 In article questions of realization of a kompetentnostny approach at ecology and natural sciences lessons at high school are considered.
A I Kurbatova
doaj
Competence Monitoring in Project Teams by using Web based portfolio management systems [PDF]
, 2011 This paper reports a learning experience related to the acquisition of project management competences. Students from three different universities and backgrounds, cooperate in a common project that drives the learning-teaching process.
Alba Elías, Fernando +3 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Cadernos EBAPE.BRRefletir sobre um conceito em construção - o conceito de competência - e o uso de estratégias interativas para aprendizagem são os objetivos deste artigo.
Maria Tereza Leme Fleury +1 more
doaj +1 more source
Competence – based approach in training masters for water management
Водное хозяйство России: проблемы, технологии, управление, 2022 Objectives of this work has been determined by the world-wide water resources quality deterioration and increase of the signifi cance of experts capable not only of designing and building of the industrial/drinking water treatment systems, waste water ...
Olga Naschetnikova +6 more
doaj +1 more source
Three Algorithms for Competence-Oriented Anaphor Resolution [PDF]
, 2005 In the last decade, much effort went into the design of robust third-person pronominal anaphor resolution algorithms. Typical approaches are reported to achieve an accuracy of 60-85%.
Stuckardt, Roland
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Efektivitas Pendekatan Scientific dengan Pbl dan Problem Solving untuk Meningkatkan Kompetensi dalam Pembelajaran IPS [PDF]
, 2016 This study aimed to compare the effectiveness of scientific approach with problem based learning and problem solving in teaching social studies to improve: attitude competence, knowledge competene, and skill competence.The population of the research was ...
Mulyani, E. (Endang) +1 more
core