Results 41 to 50 of about 190,632 (269)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Conceptual apparatus formation of the problem of building of communicative reflection of future specialists

Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2019
The article is dedicated to the formation of the problem of building of communicative reflection of future specialists through the prism of historical aspect.
Svetlana V. Sannikova
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Foreign language communicative competence forming of students studying at food production department (by the example of text book “food technology”)

Вестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2016
The article considers a problem of foreign-language communicative competence forming. Authors believe that training of foreign-language communicative activities with use of course book Food Technology helps students to use and understand foreign-language
Anna A. Khokhlova, Amaliya L. Kuregyan
doaj  

Approaches to the Design and Updating of Educational Programs Competence Models Based on the Intellectual Analysis of Employers’ Vacancies

Управленческое консультирование, 2023
The general logic of the formation of competence models in the interaction of labor market subjects and vocational education institutions is analyzed.
D. V. Minaev
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Operationalization of Competency-Based Approach: From Competency-Based Education to Integration Pedagogy

, 2017
Advocates of integration pedagogy such as Peyser et al. (2006) and Roegiers (2010) consider this instructional approach as a distinct pedagogical trend, while opponents of this view such as Hirtt (2009) regard integration pedagogy and competency-based education (CBE) as two sides of the same coin.
Arab World English Journal, Slimane BOUKHENTACHE   +1 more
openaire   +2 more sources

TEACHING WITHIN THE COMPETENCY- BASED APPROACH

RIMAK International Journal of Humanities and Social Sciences, 2021
The Education Sector is Considered One of The Most Important Issues That Have Occupied The Minde Of Many Schoalrs And Researchers, given its Importance At The Global And National Level, As It Is An Essential And Effective Element in building and developing Countries And Advancing Societies.
Samir NOUIRI, Sabrina RAMASH
openaire   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Application of a method of case technologies in the education system at high school on an example of a lesson of ecology

RUDN Journal of Ecology and Life Safety, 2012
In article questions of realization of a kompetentnostny approach at ecology and natural sciences lessons at high school are considered.
A I Kurbatova
doaj