Results 51 to 60 of about 29,264,869 (300)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The integrated view on competence

open access: yes, 2022
This chapter begins with an outline of the main features of an integrated understanding of competence and how this understanding differs from some other common approaches to competence. Inspired by behaviourism, much competency-based training (CBT) views
Hager, P
core   +1 more source

Foreign language communicative competence forming of students studying at food production department (by the example of text book “food technology”)

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2016
The article considers a problem of foreign-language communicative competence forming. Authors believe that training of foreign-language communicative activities with use of course book Food Technology helps students to use and understand foreign-language
Anna A. Khokhlova, Amaliya L. Kuregyan
doaj  

Approaches to the Design and Updating of Educational Programs Competence Models Based on the Intellectual Analysis of Employers’ Vacancies

open access: yesУправленческое консультирование, 2023
The general logic of the formation of competence models in the interaction of labor market subjects and vocational education institutions is analyzed.
D. V. Minaev
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Operationalization of Competency-Based Approach: From Competency-Based Education to Integration Pedagogy

open access: yes, 2017
Advocates of integration pedagogy such as Peyser et al. (2006) and Roegiers (2010) consider this instructional approach as a distinct pedagogical trend, while opponents of this view such as Hirtt (2009) regard integration pedagogy and competency-based education (CBE) as two sides of the same coin.
Arab World English Journal   +1 more
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Competence-based training and assessment by portfolio: the health psychology model [PDF]

open access: yes, 2007
All UK postgraduate qualifications in applied areas of psychology will soon be competence-based. This will improve the professional recognition and esteem of applied psychology, and make it easier to transfer qualifications between psychology and other ...
James Elander   +8 more
core   +1 more source

Application of a method of case technologies in the education system at high school on an example of a lesson of ecology

open access: yesRUDN Journal of Ecology and Life Safety, 2012
In article questions of realization of a kompetentnostny approach at ecology and natural sciences lessons at high school are considered.
A I Kurbatova
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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