Results 261 to 270 of about 992,860 (360)

m6A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post‐Transcriptional Control

Advanced Science, EarlyView.
As an m6A reader, hnRNPA2B1 predominantly regulates specific transcripts (e.g., Ep400, Rrs1) that are essential for chromosome organization and remodeling in an m6A‐dependent manner. Furthermore, it is demonstrated to interact with factors involved in mRNA processing and translation. This dual functionality is pivotal for ensuring the proper occurrence
Lisha Yin, Yuting Zhang, Bingqian Zhang, Jin Zhang, Mengneng Xiong, Nan Jiang, Jinxin Xiao, Huihui Gao, Wenjing Xiong, Xiaoli Wang, Fengli Wang, Shuiqiao Yuan   +11 more
wiley   +1 more source

Relationship between death anxiety and coping with death competence among Chinese oncology nurses: A chain mediation model. [PDF]

World J Psychiatry
Wen Y, Zhang QX, Liu Y, He XH, Gong YW.
europepmc   +1 more source

Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
The aberrant adenosine metabolism leads to chemoresistance and immunosuppressive microenvironment. A versatile albumin‐polyplexes conjugated nanoparticle B‐PDEA@CPA is prepare for the codelivery of gemcitabine and siCD39. The nanoparticle releases gemcitabine‐loaded albumin upon microenvironment to achieve promoted penetration and cellular uptake ...
Hongrui Fan, Hongyi Chen, Haolin Song, Chufeng Li, Yu Wang, Zhenhao Zhao, Qin Guo, Xuwen Li, Mingxuan Liu, Tao Sun, Chen Jiang   +10 more
wiley   +1 more source

Measuring Managerial, Collegial, and Organizational Aspects Associated With Digital Health Competence in Healthcare Professionals: Validation of the Chinese Version of the DigiComInf Instrument. [PDF]

J Nurs Manag
Gao L, Wang J, Chen M, Wei J, Liao X.
europepmc   +1 more source

Low‐Power Tunable Micro‐Plasma Device for Efficient and Scalable CO2 Valorization

Advanced Science, EarlyView.
Tunable in‐chip micro‐plasma generation leads to efficient, low‐power and scalable CO2 valorization under atmospheric pressure via vibrational excitation mechanism. Abstract Valorizing CO2 into chemical building blocks via efficient electrified processes could significantly decrease carbon emissions.
Bartu Karakurt, Hongkeng Zhu, Onder Soydal, Guangyu Sun, Jeremy S. Luterbacher, Elison Matioli   +5 more
wiley   +1 more source

Analyzing the network structure of students' motivation to learn AI: a self-determination theory perspective. [PDF]

NPJ Sci Learn
Li J, Zhang J, Chai CS, Lee VWY, Zhai X, Wang X, King RB.   +6 more
europepmc   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source

Prednisolone at a therapeutic dose is not detrimental to mouse oocyte competence. [PDF]

JBRA Assist Reprod
Muthukumar S, Shetty V, Daddangadi A, Adiga SK, Uppangala S.   +4 more
europepmc   +1 more source

Hydrogen‐Deuterium Exchange Mass Spectrometry for Molecular Glue Characterization

Advanced Science, EarlyView.
Molecular glues that stabilize protein–protein interactions are challenging to identify. Here, hydrogen‐deuterium exchange mass spectrometry can show and reveal gluing mechanisms that vary between protein binding partners. Abstract Molecular glues are powerful bioactive molecules that stabilize protein–protein interactions.
Danielle F. Kay, Hadeeqa G. Raza, Richard G. Doveston, Aneika C. Leney   +3 more
wiley   +1 more source

Cross-sectional associations between intrinsic and extrinsic motivation for physical activity and body composition in adolescents with obesity. [PDF]

Obes Pillars
de Freitas F, Zago MR, Antônio MÂ, Videira-Silva A, Bellomo Brandão MÂ.   +4 more
europepmc   +1 more source