Results 61 to 70 of about 1,368,769 (288)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The approach to formation of the competence component structure

Высшее образование в России, 2022
This article focuses on the methodical solutions for formation of the basic educational programs, which are constructed on the Federal state educational standards of the third generation.
Efim L. Kon, Vladimir I. Freyman, Aleksandr A. Yuzhakov, Ekaterina M. Kon   +3 more
doaj  

Forecasting Construction Engineering Students’ Learning Outcomes by Means of Computational Pedagogys

Интеграция образования, 2020
Introduction. The prediction of learning outcomes plays an important role in professional training of the future civil engineers. The relevance of the article lies in the lack of a unified approach to predicting the formation of basic professional ...
Juriy A. Tashkinov
doaj   +1 more source

Parallel Distributed Grammar Engineering for Practical Applications [PDF]

, 2011
Based on a detailed case study of parallel grammar development distributed across two sites, we review some of the requirements for regression testing in grammar engineering, summarize our approach to systematic competence and performance profiling, and ...
Bender, Emily M., Callmeier, Uli, Flickinger, Dan, Oepen, Stephan, Siegel, Melanie   +4 more
core  

THERAPEUTIC SUPPORT OF REALIZATION OF THE COMPETENCE APPROACH IN EDUCATION

Інформаційні технології і засоби навчання, 2010
The article analyses mechanisms of realization of the competence approach in education. Its therapeutic support actualizes factors of nonlinearity, processuality, subjectivity, conformity with nature, feedback in the educational environment.
Viktoriia A. Lykova
doaj  

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

IDENTIFICATION OF INFORMATION AND COMMUNICATION COMPETENCES

Інформаційні технології і засоби навчання, 2010
Article is devoted to identification of information and communication competence and levels of their formation of the future teachers of informatics. It examines the different approaches to the problem of criteria for evaluating competence, describes the
Oleksandr M. Kryvonos
doaj  

RUSSIAN LANGUAGE EDUCATION STRATEGY HOW TO TEACH CHINESE STUDENTS IN THE SOCIAL AND CULTURAL SPACE OF REPUBLIC OF SAKHA (YAKUTIA)

Sovremennye Issledovaniâ Socialʹnyh Problem, 2015
This article presents main problems of the studying Russian as foreign to Chinese students in the social and cultural space of republic of Sakha (Yakutia). There are specific difficulties of learning Chinese students and ways of solving problems.
Sakhaya Nurgunovna Alexandrova
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source