Results 51 to 60 of about 1,579,148 (310)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Curiosity and its role in cross-cultural knowledge creation [PDF]

open access: yes, 2016
This paper explores the role of curiosity in promoting cross-cultural knowledge creation and competence development. It is based on a study with four international higher educational institutions, all of which offer management and business education ...
Mikhaylov, Natalie S.
core   +1 more source

Global Gene Expression Profiling of Individual Human Oocytes and Embryos Demonstrates Heterogeneity in Early Development [PDF]

open access: yes, 2013
Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals.
Brison, Daniel R.   +4 more
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

DE PROFESSOR A CHEFE DE DEPARTAMENTO: UM ESTUDO SOBRE O DESENVOLVIMENTO DAS COMPETÊNCIAS GERENCIAIS DESSES PROFISSIONAIS NUMA UNIVERSIDADE PÚBLICA

open access: yesRevista Gestão Universitária na América Latina, 2018
This basic interpretative and qualitative research answers how professors from Dentistry School in Araçatuba/UNESP develop their management skills to act as university head of department, that is, what these professors understand by being a competent ...
Diogo Reatto, Janette Brunstein
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Implementation of online peer feedback for student self-reflection – first steps on the development of a feedback culture at a medical faculty

open access: yesGMS Journal for Medical Education, 2019
Objective: Acquisition and application of professional and personal competences is accompanied by the formation and consolidation of attitudes and values and is influenced by the norms and moods (trust and feedback culture) experienced in the learning ...
Raski, Bianca   +6 more
doaj   +1 more source

Використання хмарних обчислень для розвитку інформаційно-комунікаційної компетентності вчителів [PDF]

open access: yes, 2013
The article deals with the problem for development of techers’ information and communication competence and use of cloud computing for it. The analysis of the modern approaches to the use of cloud technologies and projects for professional development of
Сороко, Н.В.   +1 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The development of the digital teaching competence from a sociocultural approach [PDF]

open access: yes, 2019
En la actualidad, la competencia digital docente trasciende de la formación individual del profesorado en materia TIC. El marco europeo DigCompEdu incide en que el profesorado tiene que capacitar al alumnado en la aplicación de las tecnologías digitales ...
Colás Bravo, María Pilar   +2 more
core   +2 more sources

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