Results 101 to 110 of about 1,185,920 (393)

Digital Literacy Circulation: Adolescents and Flows of Knowledge about New Media [PDF]

open access: yes, 2016
The aim of this paper is to discuss the output of an empirical research on digital skills in order to develop a typology of skills circulation among young digital users.
Riva, Claudio, Scarcelli, Cosimo Marco
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The competence approach as the basis to form training system for library professionals in the Republic of Cameroon

open access: yesБиблиосфера, 2019
The article deals with the attitude of specialists to the competence approach in higher education, the stages of the “competence” formation concept are shown.
J. Zemengue, T. Mbila
doaj   +1 more source

Key Competences in Europe: Opening Doors For Lifelong Learners Across the School Curriculum and Teacher Education [PDF]

open access: yes
The aim of the study is to provide a comparative overview of policy and practice concerning the development and implementation of key competences in the education systems of the 27 Member States of the European Union.
Alain Michel   +7 more
core  

Competences of IT Architects [PDF]

open access: yes, 2008
The field of architecture in the digital world uses a plethora of terms to refer to different kinds of architects, and recognises a confusing variety of competences that these architects are required to have.
Eck, Pascal van   +3 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Competences possessed and required by European graduates. REFLEX Report to HEFCE No 4 [PDF]

open access: yes, 2008
The report is based on the results of a major international study of graduate employment some five years after graduation. It presents an analysis of graduates' perceptions of what competences they need to do their current jobs and whether they possess ...
Braun, Edith   +2 more
core  

Developing Project Managers’ Transversal Competences Using Building Information Modeling [PDF]

open access: yes, 2019
The emergence of building information modeling (BIM) methodology requires the training of professionals with both specific and transversal skills. In this paper, a project-based learning experience carried out in the context of a project management ...
García Sanz-Calcedo, Justo   +3 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Competence and competence development [PDF]

open access: yes, 2012
What are today's main concepts and theories - and the main stakes - associated with the issue of competences in organizations? Several topics are discussed, including competence issues regarding the evolution of work, professionalization, competence evaluation, competence management, and the competences of adult educators and trainers, as well as ...
openaire   +2 more sources

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