Results 61 to 70 of about 36,353 (268)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Occupational dimension of the INFODORADCA+ project [PDF]

open access: yesEdukacja Ustawiczna Dorosłych, 2019
Knowledge about occupations – professionalization, is a basic element of work pedagogy. It allows for professional observation of the process of professional tasks implementation, and then for assigning to each distinguished task a set of ...
Stefan Kwiatkowski
doaj  

THE INTELLECTUAL CAPITAL OF AN ORGANIZATION AS AN ECONOMIC RESOURCE FOR INNOVATION BUSINESS

open access: yesВестник Северо-Кавказского федерального университета, 2022
The paper discusses the role of intellectual capital and competences in arising and enhancement of contemporary innovation business. It stresses the crucial impact of knowledge management system on ascendance of organizations’ competitiveness.
Robert M. Nizhegorodtsev   +2 more
doaj  

Experience in teaching the course “Theory and Methodology of Education”at the Rivne State Humanitarian University (Ukraine): good practices and challenges [PDF]

open access: yesStudia z Teorii Wychowania
Reforming the system of higher education in Ukraine has set requirements for changes in approaches, paradigms, content and forms of work with students, including pedagogical specialties. Forced changes in the teaching of future teachers took place during
Iryna Androshchuk, Oksana Petrenko
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Regional odontodysplasia: a report of unusual case with in-depth analysis

open access: yesJournal of Oral Biology and Craniofacial Research
Background/purpose: Regional odontodysplasia (RO) is a rare developmental anomaly affecting dental tissue formation, typically confined to a single quadrant.
Charles Béhot   +6 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Study of Endocrine-Disrupting Chemicals in Infant Formulas and Baby Bottles: Data from the European LIFE-MILCH PROJECT

open access: yesMolecules
Exposure to endocrine-disrupting chemicals (EDCs) is inevitable, and growing scientific evidence indicates that even very low doses can negatively impact human health, particularly during pregnancy and the neonatal period. As part of the European project
Francesca Nuti   +8 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Przedsiębiorczość polskich prawników

open access: yesStudia i Materiały, 2015
Polish legal services market is developing fast. The role of Polish lawyers has changed and they are often seen as entrepreneurs who need to compete for customers, not only as professionals.
Marek Gnusowski
doaj   +1 more source

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