Results 131 to 140 of about 28,432,988 (289)

Competency-based medical education

open access: yesIndian Journal of Psychiatry, 2021
Sethi, Sujata   +2 more
openaire   +3 more sources

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang   +11 more
wiley   +1 more source

Competency-Based Education (CBE) [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2006
A Yousefi
doaj  

Consequence in Competency-Based Education: Individualize, but Do Not Compromise. [PDF]

open access: yesJ Gen Intern Med, 2022
Gielissen K, Logio L, Qua K, Hemmer P.
europepmc   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn   +20 more
wiley   +1 more source

Hyperpolarization of [1‐13C]Ketoisocaproate‐d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched‐Chain‐Amino‐Acid Metabolism in Cellulo and in Vivo

open access: yesAdvanced Science, EarlyView.
We report the fast generation of biocompatible solutions of highly 13C‐hyperpolarized (≈11%) partially‐deuterated ketoisocaproate within <6 min using spin‐lock‐induced crossing and reversible exchange with parahydrogen (SLIC‐SABRE). This enables rapid detection of branched‐chain‐amino‐acid transferase 1 (BCAT1) protein expression and investigation of ...
Stefan Petersen   +18 more
wiley   +1 more source

American Board of Orthopaedic Surgery's Initiatives Toward Competency-Based Education. [PDF]

open access: yesJB JS Open Access, 2022
Van Heest AE   +12 more
europepmc   +1 more source

A Generative Neuro‐Symbolic AI for Protein Sequence Design

open access: yesAdvanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne   +12 more
wiley   +1 more source

Competency-Based Medical Education: Establishing A Framework for Lifelong Learning [PDF]

open access: yesآموزش پزشکی
letter to the editor does not require an abstract.
Hamid Mahdavifard
doaj  

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