Results 171 to 180 of about 530,705 (304)

The significance of competencies in corporate competitiveness and in education [PDF]

Human resources (hereinafter referred to as HR) have always been playing a decisive role in economic life. The company’s competitiveness, success and market position greatly depends on its human factor organising and running it from the background ...
Erika Varga, László Áron Kóczy, Mónika Fodor, Ágnes Csiszárik-Kocsir   +3 more
core  

Targeting the PGRN‐BMP Lysosomal Axis With NPs@PGRN Reverses Immunometabolic Dysfunction in Chronic Septic Arthritis

Advanced Science, EarlyView.
Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li, Jiaqi Fan, Tao Sun, Wushi Cui, Jiaxuan Zou, Weinan Yang, Liang Chen, Jian Xiao, Shicheng Wang, Tao Zhang, Jianqiao Hong, An Liu, Haobo Wu   +12 more
wiley   +1 more source

Competency-based education in intensive care multiprofessional training: a scoping review. [PDF]

Crit Care Sci
Gomes TO, Girão FB, Silva MH, Andrade MVM.   +3 more
europepmc   +1 more source

Pedagogically informed metadata content and structure for learning and teaching

, 2007
In order to be able to search, compare, gap analyse, recommend, and visualise learning objects, learning resources, or teaching assets, the metadata structure and content must be able to support pedagogically informed reasoning, inference, and machine ...
Gilbert, Lester, Sitthisak, Onjira
core  

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Transitioning to competency-based education in nursing: a scoping review of curriculum review and revision strategies. [PDF]

BMC Nurs
Mani ZA.
europepmc   +1 more source

Pediatric Chronic Tracheostomy Care: An Evaluation of an Innovative Competency-Based Education Program for Community Health Care Providers. [PDF]

Front Pediatr, 2022
Shi JY, Orkin J, Walsh CM, Chu S, Keilty K, McKay S, Mocanu C, Qazi A, Ambreen M, Amin R.   +9 more
europepmc   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Clinical assessment strategies for competency-based education in prosthetic dentistry. [PDF]

J Dent Educ
Khan SB, Maart R.
europepmc   +1 more source

PENDIDIKAN KEWARGANEGARAANPERSEKOLAHAN: STANDARISI DAN PEMBELAJARANNYA [PDF]

The content standard of civic education for the elementary level and junior high level consist of minimum materials and minimum competency, there are standard competency and basic competency of civic education subject that should be studied by the
Winarno, -
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