Results 231 to 240 of about 1,232,754 (357)

Endothelial PD‐1 Regulates Vascular Homeostasis and Oligodendrogenesis during Brain Development

Advanced Science, EarlyView.
Vascular endothelial cells are fundamental for angiogenesis and brain development. This study reveals that endothelial programmed cell death 1 (PD‐1) is critical for cerebral angiogenesis and blood brain barrier (BBB) maturation. It also mediates interaction with oligodendrocyte precursor cells (OPCs), modulating OPCs differentiation and myelination ...
Tingting He, Mengtian Zhang, Jie Qin, Yanyan Wang, Sihan Li, Chaoyi Du, Jianwei Jiao, Fen Ji   +7 more
wiley   +1 more source

Developing a competency assessment framework for pharmacists in primary health care settings in India. [PDF]

PLoS One
Kumar S, Bhoi P, Gharat MS, Mohanta GP.
europepmc   +1 more source

The use of the ultracentrifuge to determine the catalytically competent forms of enzymes with more than one oligomeric structure. Multiple reacting forms of pyruvate carboxylase from chicken and rat liver.

, 1978
Barry Taylor, William H. Frey, R E Barden, M.C. Scrutton, M.F. Utter   +4 more
openalex   +1 more source

Competencies for Middle School Teaching: A Review of Empirical Studies of Teacher Effects [PDF]

, 1977
David Strahan
openalex   +1 more source

Engineered Genetic Circuits Activated by Bezafibrate Improve ESC‐Based TAA Cancer Vaccine Efficacy and PD‐L1 Nanobody Therapy

Advanced Science, EarlyView.
Synthetic gene circuits regulated by bezafibrate are developed to express tumor antigens and PD‐L1 nanobody (PD‐L1nb), enhancing cancer immunotherapy. Delivered via HEK293T cells, ESCs, or directly injected the plasmids containing the circuit into the tumor, the circuits reduce tumor growth, boost CD8+ T cells, and minimize T cell exhaustion.
Meiling Jin, Shuzhen Liu, Mingshuo Zhan, Jian‐Dong Huang   +3 more
wiley   +1 more source

Advancing home health nursing competencies in Canada to reflect a dynamic care environment and complex population health needs: a modified eDelphi study. [PDF]

BMC Nurs
Saari M, Coumoundouros C, Tadeo J, Chyzzy B, Northwood M, Giosa J.   +5 more
europepmc   +1 more source

Evidence that carboxyphosphate is a kinetically competent intermediate in the carbamyl phosphate synthetase reaction.

, 1979
M.J. Wimmer, I A Rose, S G Powers, A Meister   +3 more
openalex   +1 more source

Replicating PET Hydrolytic Activity by Positioning Active Sites with Smaller Synthetic Protein Scaffolds

Advanced Science, EarlyView.
A workflow is proposed for the computational design of new‐to‐nature PET hydrolases by remodeling the protein scaffold. Starting from the functional motifs extracted from a template enzyme, designer enzymes are generated following four steps: scaffold remodeling, computational screening, experimental validation, and sequence refinement.
Yujing Ding, Shanshan Zhang, Xian Kong, Henry Hess, Yifei Zhang   +4 more
wiley   +1 more source

Stfm Announces New Point of Care Ultrasound Task Force and Initiative on POCUS Family Medicine Education. [PDF]

Ann Fam Med
Paulus R, Davies A.
europepmc   +1 more source

Medical Education : The Challenge to educate Competent Physician [PDF]

, 1970
Joseph S. Gonnella
openalex   +1 more source